Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ULK1 | O75385 | 2/20 | 0.56 |
| ▸ | CDK9 | P50750 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | AAK1 | Q2M2I8 | 7/20 | 0.48 |
| ▸ | GSK3A | P49840 | 7/20 | 0.47 |
| ▸ | GSK3B | P49841 | 7/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.47 |
| ▸ | TYK2 | P29597 | 1/20 | 0.47 |
| ▸ | CDK2 | P24941 | 2/20 | 0.45 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.45 |
| ▸ | PIM1 | P11309 | 1/20 | 0.45 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26396687 | 1.00 | ULK1 (0.56) | ULK1CDK9HDAC6AAK1GSK3A | |
| SCHEMBL26396531 | 1.00 | ULK1 (0.56) | ULK1CDK9HDAC6AAK1GSK3A | |
| Hydrochloric Acid SCHEMBL26127100 | 0.99 | ULK1 (0.55) | ULK1CDK9HDAC6AAK1GSK3A | |
| Hydrochloric Acid SCHEMBL26129521 | 0.99 | ULK1 (0.55) | ULK1CDK9HDAC6AAK1GSK3A | |
| Hydrochloric Acid SCHEMBL26131725 | 0.99 | ULK1 (0.55) | ULK1CDK9HDAC6AAK1GSK3A | |
| SCHEMBL26396673 | 0.95 | GSK3A (0.50) | ULK1HDAC6AAK1GSK3AGSK3B | |
| SCHEMBL26396659 | 0.95 | GSK3A (0.50) | ULK1HDAC6AAK1GSK3AGSK3B | |
| SCHEMBL26396667 | 0.95 | GSK3A (0.50) | ULK1HDAC6AAK1GSK3AGSK3B | |
| Hydrochloric Acid SCHEMBL26127634 | 0.94 | GSK3A (0.49) | ULK1HDAC6AAK1GSK3AGSK3B | |
| Hydrochloric Acid SCHEMBL26130464 | 0.94 | GSK3A (0.49) | ULK1HDAC6AAK1GSK3AGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023186773-A1 | SUBSTITUTED 3-AMINO INDAZOLE DERIVATIVES AS KINASE INHIBITORS | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2023-10-05 | — | — | WO | disclosed |