Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | EDNRB | P24530 | 1/20 | 0.36 |
| ▸ | EDNRA | P25101 | 1/20 | 0.36 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | FPR3 | P25089 | 1/20 | 0.35 |
| ▸ | FPR2 | P25090 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25651 | 0.80 | CA12 (0.47) | LMNAKMT2A | |
| SCHEMBL31055970 | 0.79 | PBRM1 (0.46) | LMNAGAAKMT2AKDM4EEDNRB | |
| SCHEMBL31371502 | 0.77 | GAA (0.42) | LMNAGAAKDM4EEDNRBEDNRA | |
| SCHEMBL31371464 | 0.74 | KDM4E (0.60) | LMNAGAAKDM4EEDNRBEDNRA | |
| SCHEMBL17144723 | 0.71 | EDNRB (0.43) | KMT2AEDNRBEDNRAPBRM1SMN1; SMN2 | |
| SCHEMBL18421257 | 0.71 | GAA (0.41) | GAAKMT2AEDNRBEDNRAPBRM1 | |
| SCHEMBL18421246 | 0.71 | GAA (0.41) | GAAKMT2AEDNRBEDNRAPBRM1 | |
| SCHEMBL17144989 | 0.71 | GAA (0.41) | GAAKMT2AEDNRBEDNRAPBRM1 | |
| SCHEMBL18805600 | 0.67 | GAA (0.49) | LMNAGAAKDM4ERAB9ANPC1 | |
| SCHEMBL28108235 | 0.66 | PBRM1 (0.46) | LMNAKMT2AEDNRBEDNRAPBRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012026403-A1 | CONDENSED RING COMPOUND | 日本曹達株式会社 (JP) | 2012-03-01 | — | — | WO | disclosed |