Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA7 | P43166 | 2/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.40 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30985352 | 0.85 | CA12 (0.55) | CA12CA7CA14TRPV1HDAC6 | |
| SCHEMBL22516689 | 0.85 | CA12 (0.55) | CA12CA7CA14TRPV1HDAC6 | |
| SCHEMBL26295 | 0.83 | CA12 (0.46) | CA12CA7CA14HDAC6HDAC3 | |
| SCHEMBL1787681 | 0.83 | CA12 (0.49) | CA12CA7CA14TRPV1CA1 | |
| SCHEMBL22517019 | 0.81 | CA12 (0.56) | CA12CA7CA14TRPV1HDAC6 | |
| SCHEMBL22517090 | 0.81 | CA12 (0.58) | CA12CA7CA14TRPV1HDAC6 | |
| SCHEMBL22500094 | 0.81 | CA12 (0.55) | CA12CA7CA14TRPV1HDAC6 | |
| SCHEMBL33088 | 0.80 | CA12 (0.43) | CA12CA7CA14HDAC6HDAC3 | |
| SCHEMBL26397 | 0.80 | LMNA (0.39) | KMT2ALMNA | |
| SCHEMBL25347 | 0.79 | CA12 (0.63) | CA12CA7CA14TRPV1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012026403-A1 | CONDENSED RING COMPOUND | 日本曹達株式会社 (JP) | 2012-03-01 | — | — | WO | disclosed |