Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 2/20 | 1.00 |
| ▸ | LCK | P06239 | 2/20 | 1.00 |
| ▸ | FYN | P06241 | 1/20 | 1.00 |
| ▸ | GRB2 | P62993 | 1/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.70 |
| ▸ | GAA | P10253 | 2/20 | 0.70 |
| ▸ | GLA | P06280 | 1/20 | 0.70 |
| ▸ | HSD17B3 | P37058 | 9/20 | 0.69 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.68 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30643728 | 0.88 | AKR1B1 (0.78) | AKR1B1LCKFYNGRB2KDM4E | |
| SCHEMBL23125054 | 0.88 | AKR1B1 (0.78) | AKR1B1LCKFYNGRB2KDM4E | |
| SCHEMBL723839 | 0.86 | LCK (0.76) | AKR1B1LCKFYNGRB2KDM4E | |
| SCHEMBL13840541 | 0.86 | AKR1B1 (0.76) | AKR1B1LCKFYNGRB2KDM4E | |
| SCHEMBL12729968 | 0.86 | AKR1B1 (0.76) | AKR1B1LCKFYNGRB2KDM4E | |
| SCHEMBL23326972 | 0.85 | LCK (0.73) | AKR1B1LCKFYNGRB2KDM4E | |
| SCHEMBL2791708 | 0.85 | AKR1B1 (0.74) | AKR1B1LCKFYNGRB2KDM4E | |
| SCHEMBL13839157 | 0.84 | AKR1B1 (0.72) | AKR1B1LCKFYNGRB2KDM4E | |
| SCHEMBL17403166 | 0.84 | AKR1B1 (0.72) | AKR1B1LCKFYNGRB2KDM4E | |
| SCHEMBL14341910 | 0.83 | LCK (0.71) | AKR1B1LCKFYNGRB2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 344 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4661890-A1 | PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS | Purdue Research Foundation (US) | 2025-12-17 | — | — | EP | claimed |
| CN-116874458-B | Coumarin fluorescent probe based on benzotrifluoride derivative and application thereof | 常州大学 | 2025-05-27 | — | — | CN | claimed |
| CN-119431294-A | Fluorescent probe for tracking micro-environmental changes before and after ischemia reperfusion injury treatment and preparation method and application thereof | 新乡医学院 | 2025-02-14 | — | — | CN | claimed |
| WO-2024167565-A1 | PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS | PURDUE RESEARCH FOUNDATION (US) | 2024-08-15 | — | — | WO | claimed |
| EP-2904385-B1 | INDICATOR DEVICE | INSIGNIA TECH LTD (GB) | 2023-11-29 | — | — | EP | claimed |
| CN-116874458-A | Coumarin fluorescent probe based on benzotrifluoride derivative and application thereof | 常州大学 | 2023-10-13 | — | — | CN | claimed |
| CN-114507204-B | Golgi apparatus targeted superoxide anion fluorescent probe, preparation method and application thereof | 南华大学 | 2023-06-02 | — | — | CN | claimed |
| EP-3469353-B1 | INDICATOR DEVICE | INSIGNIA TECH LIMITED (GB) | 2022-09-07 | — | — | EP | claimed |
| EP-4044211-A1 | MALDI-MS METHOD, PHOTO-SENSITIVE MALDI MATRIX COMPOSITE AND PHOTO-CAGED MALDI MATRIX COMPOUND FOR USE IN SAID METHOD AND RESPECTIVE USES | Sirius Fine Chemicals SiChem GmbH (DE) | 2022-08-17 | — | — | EP | claimed |
| US-11371974-B2 | Indicator device | INSIGNIA TECHNOLOGIES LIMITED (GB) | 2022-06-28 | — | — | US | claimed |
| WO-2009015268-A2 | ENGINEERED GLYCOSYLTRANSFERASES WITH EXPANDED SUBSTRATE SPECIFICITY | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2009-01-29 | — | — | WO | claimed |
| WO-2007115181-A9 | COMPOUNDS EXHIBITING EFFLUX INHIBITOR ACTIVITY AND COMPOSITIONS AND USES THEREOF | EASTMAN CHEM CO (US) | 2008-04-03 | — | — | WO | claimed |
| US-20070254859-A1 | Compounds exhibiting efflux inhibitor activity and composition and uses thereof | EASTMAN CHEMICAL COMPANY | 2007-11-01 | — | — | US | claimed |
| WO-2007115181-A2 | COMPOUNDS EXHIBITING EFFLUX INHIBITOR ACTIVITY AND COMPOSITIONS AND USES THEREOF | EASTMAN CHEMICAL COMPANY (US) | 2007-10-11 | — | — | WO | claimed |
| WO-2000022909-A2 | SYSTEMS FOR ORAL DELIVERY | BIOTECH AUSTRALIA PTY. LIMITED (AU) | 2000-04-27 | — | — | WO | claimed |
| US-5854008-A | Europium and terbium chelators for the time-resolved fluorometric assays | NORDION INTERNATIONAL, INC. (CA) | 1998-12-29 | — | — | US | claimed |
| EP-0244929-B1 | Fluorescent polymeric indicator sensor | HOWMEDICA (US) | 1994-04-20 | — | — | EP | claimed |
| WO-1992020821-A1 | cDNA-PHOTOFLUOR PROBE AND METHODS OF MAKING, ASSAYING AND USING SAME | PHARMACEUTICAL DISCOVERY CORPORATION (US) | 1992-11-26 | — | — | WO | claimed |
| US-5019350-A | Esterified or aminated addition polymers | PFIZER HOSPITAL PRODUCTS, INC. (US) | 1991-05-28 | — | — | US | claimed |
| EP-0244929-A2 | Fluorescent polymeric indicator sensor | HOWMEDICA INC. (US) | 1987-11-11 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070254859-A1 | Compounds exhibiting efflux inhibitor activity and composition and uses thereof | ABCC4, NCOA4, NR4A3 | AKR1B1 384/4885LCK 2613/4885FYN 702/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.