Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 18/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | FADS1 | O60427 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28000228 | 0.82 | PDE3B (0.44) | GSK3BFADS1 | |
| SCHEMBL5583100 | 0.81 | HDAC6 (0.43) | LRRK2GSK3B | |
| SCHEMBL2661165 | 0.80 | BTK (0.51) | LRRK2 | |
| SCHEMBL23867179 | 0.80 | LRRK2 (0.51) | LRRK2 | |
| SCHEMBL26399495 | 0.79 | TTK (0.59) | LRRK2FADS1 | |
| SCHEMBL16011905 | 0.78 | LRRK2 (0.47) | LRRK2 | |
| SCHEMBL26133172 | 0.78 | LRRK2 (0.47) | LRRK2 | |
| SCHEMBL2660492 | 0.77 | GRM4 (0.51) | LRRK2FADS1 | |
| SCHEMBL26399519 | 0.77 | TTK (0.47) | FADS1 | |
| SCHEMBL24638445 | 0.76 | PRKAG1 (0.46) | LRRK2GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023186773-A1 | SUBSTITUTED 3-AMINO INDAZOLE DERIVATIVES AS KINASE INHIBITORS | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2023-10-05 | — | — | WO | disclosed |