Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 18/20 | 0.67 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4666420 | 0.91 | S1PR1 (0.64) | S1PR1FFAR1 | |
| SCHEMBL2638267 | 0.89 | S1PR1 (0.66) | S1PR1S1PR3 | |
| SCHEMBL2638801 | 0.88 | S1PR1 (0.53) | S1PR1S1PR3 | |
| SCHEMBL2639905 | 0.86 | S1PR1 (0.67) | S1PR1S1PR3FFAR1 | |
| SCHEMBL4666263 | 0.85 | S1PR1 (0.50) | S1PR1S1PR3 | |
| SCHEMBL2639815 | 0.85 | S1PR1 (0.73) | S1PR1S1PR3 | |
| SCHEMBL4663090 | 0.84 | S1PR1 (0.52) | S1PR1S1PR3FFAR1 | |
| SCHEMBL2638750 | 0.84 | S1PR1 (0.56) | S1PR1FFAR1 | |
| SCHEMBL2639169 | 0.83 | S1PR1 (0.53) | S1PR1 | |
| SCHEMBL2638114 | 0.83 | S1PR1 (0.54) | S1PR1S1PR3FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4700616-B2 | — | — | 2011-06-15 | — | — | JP | claimed |
| EP-1633336-A4 | IMMUNOSUPPRESSANT COMPOUNDS AND COMPOSITIONS | IRM LLC (BM) | 2008-10-29 | — | — | EP | claimed |
| EP-1633336-A2 | IMMUNOSUPPRESSANT COMPOUNDS AND COMPOSITIONS | IRM LLC (BM) | 2006-03-15 | — | — | EP | claimed |
| WO-2004103306-A2 | IMMUNOSUPPRESSANT COMPOUNDS AND COMPOSITIONS | IRM LLC (BM) | 2004-12-02 | — | — | WO | claimed |