Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.45 |
| ▸ | RIPK1 | Q13546 | 4/20 | 0.32 |
| ▸ | POLRMT | O00411 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26206219 | 0.93 | TMPRSS2 (0.44) | TMPRSS2RIPK1 | |
| SCHEMBL26206216 | 0.93 | TMPRSS2 (0.44) | TMPRSS2RIPK1 | |
| SCHEMBL26206387 | 0.91 | TMPRSS2 (0.45) | TMPRSS2RIPK1POLRMT | |
| SCHEMBL26206384 | 0.91 | TMPRSS2 (0.45) | TMPRSS2RIPK1POLRMT | |
| SCHEMBL26206400 | 0.90 | TMPRSS2 (0.46) | TMPRSS2RIPK1POLRMT | |
| SCHEMBL25432835 | 0.90 | TMPRSS2 (0.47) | TMPRSS2RIPK1POLRMT | |
| SCHEMBL26320737 | 0.90 | TMPRSS2 (0.47) | TMPRSS2RIPK1POLRMT | |
| SCHEMBL25381792 | 0.90 | TMPRSS2 (0.47) | TMPRSS2RIPK1POLRMT | |
| SCHEMBL24312633 | 0.90 | TMPRSS2 (0.46) | TMPRSS2RIPK1POLRMT | |
| SCHEMBL25379160 | 0.89 | TMPRSS2 (0.51) | TMPRSS2RIPK1POLRMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11780844-B2 | Compounds and methods for treatment of viral infections | GILEAD SCIENCES, INC. (US) | 2023-10-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11780844-B2 | Compounds and methods for treatment of viral infections | HAVCR2, EIF2AK2, OAT | TMPRSS2 112/4885RIPK1 4055/4885POLRMT 16/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.