Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.53 |
| ▸ | IDO1 | P14902 | 4/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 3/20 | 0.42 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.42 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.42 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26409 | 1.00 | LOXL2 (0.53) | LOXL2IDO1TSHRALDH1A1CYP2C19 | |
| SCHEMBL2268068 | 1.00 | LOXL2 (0.53) | LOXL2IDO1TSHRALDH1A1CYP2C19 | |
| SCHEMBL10522155 | 0.80 | TSHR (0.54) | TSHRALDH1A1CYP2C19POLBLMNA | |
| SCHEMBL10522164 | 0.80 | TSHR (0.54) | TSHRALDH1A1CYP2C19POLBLMNA | |
| SCHEMBL17045236 | 0.78 | LOXL2 (0.57) | LOXL2IDO1TSHRALDH1A1CYP2C19 | |
| SCHEMBL8986807 | 0.78 | LOXL2 (0.62) | LOXL2IDO1KCNJ1KCNH2 | |
| SCHEMBL11601065 | 0.78 | LOXL2 (0.62) | LOXL2IDO1KCNJ1KCNH2 | |
| SCHEMBL11369488 | 0.78 | LOXL2 (0.57) | LOXL2IDO1TSHRALDH1A1CYP2C19 | |
| SCHEMBL3844658 | 0.78 | LOXL2 (0.57) | LOXL2IDO1TSHRALDH1A1CYP2C19 | |
| SCHEMBL17045214 | 0.78 | LOXL2 (0.57) | LOXL2IDO1TSHRALDH1A1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5688913-A | OLIGOPEPTIDES AS ANTIINFLAMMATORY AGENTS | CYTEL CORPORATION (US) | 1997-11-18 | — | — | US | claimed |
| EP-0356796-A2 | Aminomethyl peptides, production process and their use as medicaments | BAYER AG (DE) | 1990-03-07 | — | — | EP | claimed |
| US-4818748-A | HYPOTENSIVE AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1989-04-04 | — | — | US | claimed |
| EP-0236874-A2 | Renin inhibitors, their production and use, as well as derivatives of amino acids and amino aldehydes | BAYER AG (DE) | 1987-09-16 | — | — | EP | claimed |
| EP-1438586-B1 | FRET PROTEASE ASSAYS FOR CLOSTRIDIAL TOXINS | ALLERGAN INC (US) | 2012-01-11 | — | — | EP | disclosed |
| EP-1901069-B1 | Fret protease assays for clostridial toxins | ALLERGAN INC (US) | 2012-01-04 | — | — | EP | disclosed |
| US-7270801-B2 | Fluorogenic or fluorescent reporter molecules and their applications for whole-cell fluorescence screening assays for caspases and other enzymes and the use thereof | CYTOVIA, INC. (US) | 2007-09-18 | — | — | US | disclosed |
| EP-1232183-B1 | PEPTIDES HAVING ANTIANGIOGENIC ACTIVITY | ABBOTT LAB (US) | 2006-01-18 | — | — | EP | disclosed |
| US-6984718-B2 | Fluorescence dyes and their applications for whole-cell fluorescence screening assays for caspases, peptidases, proteases and other enzymes and the use thereof | CYTOVIA, INC. (US) | 2006-01-10 | — | — | US | disclosed |
| US-6887890-B2 | Compounds exhibiting thrombopoietin-like activities | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2005-05-03 | — | — | US | disclosed |
| US-20040191844-A1 | Novel fluorogenic or fluorescent reporter molecules and their applications for whole-cell fluorescence screening assays for caspases and other enzymes and the use thereof | CYTOVIA, INC. (US) | 2004-09-30 | — | — | US | disclosed |
| EP-1100520-B1 | NOVEL FLUORESCENCE DYES AND THEIR APPLICATIONS FOR WHOLE CELL FLUORESCENCE SCREENING ASSAYS FOR CASPASES, PEPTIDASES, PROTEASES AND OTHER ENZYMES AND THE USE THEREOF | CYTOVIA INC (US) | 2004-09-22 | — | — | EP | disclosed |
| US-5516642-A | FOR TREATING DIABETES | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-05-14 | — | — | US | disclosed |
| US-5122610-A | Renin inhibitor intermediates | BAYER AKTIENGESELLSCHAFT (DE) | 1992-06-16 | — | — | US | disclosed |
| US-5066783-A | Antiviral peptides and means for treating herpes infections | COHEN ERIC A (CA) | 1991-11-19 | — | — | US | disclosed |
| US-5010057-A | Treatment of high blood pressure and cardiac insufficiency | BAYER AKTIENGESELLSCHAFT (DE) | 1991-04-23 | — | — | US | disclosed |
| EP-0393445-A2 | Use of peptide renin inhibitors as an agent against retrovirus | BAYER AG (DE) | 1990-10-24 | — | — | EP | disclosed |
| US-4818748-A | HYPOTENSIVE AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1989-04-04 | — | — | US | disclosed |
| EP-0236874-A2 | Renin inhibitors, their production and use, as well as derivatives of amino acids and amino aldehydes | BAYER AG (DE) | 1987-09-16 | — | — | EP | disclosed |
| US-4244944-A | OLIGOPEPTIDE OF TYROSINE, METHIONINE (OPTIONALLY OXIDIZED), GLYCINE, NITROPHENYLALANINE, PROLINAMIDE | BURROUGHS WELLCOME CO. (US) | 1981-01-13 | — | — | US | disclosed |