Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 8/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | RRM1 | P23921 | 1/20 | 0.37 |
| ▸ | ADH1B | P00325 | 1/20 | 0.37 |
| ▸ | ADH1C | P00326 | 1/20 | 0.37 |
| ▸ | ADH1A | P07327 | 1/20 | 0.37 |
| ▸ | ADH4 | P08319 | 1/20 | 0.37 |
| ▸ | ADH7 | P40394 | 1/20 | 0.37 |
| ▸ | FDPS | P14324 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10454334 | 0.91 | DNM1 (0.36) | DNM1EPHX1ALDH1A1TSHRMEN1 | |
| SCHEMBL8755422 | 0.86 | EPHX1 (0.44) | EPHX1ALDH1A1TSHRADH1BADH1C | |
| SCHEMBL9210932 | 0.86 | EPHX1 (0.44) | EPHX1ALDH1A1TSHRADH1BADH1C | |
| SCHEMBL3369982 | 0.86 | EPHX1 (0.44) | EPHX1ALDH1A1TSHRADH1BADH1C | |
| SCHEMBL8755205 | 0.86 | EPHX1 (0.44) | EPHX1ALDH1A1TSHRADH1BADH1C | |
| SCHEMBL11263408 | 0.86 | EPHX1 (0.44) | EPHX1ALDH1A1TSHRADH1BADH1C | |
| SCHEMBL9207849 | 0.86 | EPHX1 (0.44) | EPHX1ALDH1A1TSHRADH1BADH1C | |
| SCHEMBL22623546 | 0.86 | EPHX1 (0.44) | EPHX1ALDH1A1TSHRADH1BADH1C | |
| SCHEMBL21236821 | 0.86 | EPHX1 (0.44) | EPHX1ALDH1A1TSHRADH1BADH1C | |
| SCHEMBL11416088 | 0.86 | EPHX1 (0.44) | EPHX1ALDH1A1TSHRADH1BADH1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011141703-A1 | COMPOSITIONS AND METHODS FOR SILENCING APOLIPOPROTEIN B | PROTIVA BIOTHERAPEUTICS INC. (CA) | 2011-11-17 | — | — | WO | disclosed |