Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.52 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.30 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.30 |
| ▸ | KIT | P10721 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20759 | 0.88 | FFAR1 (0.64) | FFAR1PDK2DGAT1KIT | |
| SCHEMBL29582665 | 0.80 | FFAR1 (0.61) | FFAR1DGAT1 | |
| SCHEMBL1854359 | 0.80 | FFAR1 (0.61) | FFAR1PDK2DGAT1 | |
| SCHEMBL98961 | 0.79 | LPL (0.40) | FFAR1DGAT1 | |
| SCHEMBL6104470 | 0.79 | FFAR1 (0.45) | FFAR1 | |
| SCHEMBL9281960 | 0.79 | FFAR1 (0.59) | FFAR1PDK2DGAT1 | |
| Boric Acid SCHEMBL25234240 | 0.79 | FFAR1 (0.64) | FFAR1PDK2DGAT1KIT | |
| SCHEMBL27031982 | 0.78 | FFAR1 (0.56) | FFAR1DGAT1 | |
| Hydrochloric Acid SCHEMBL15656117 | 0.78 | LPL (0.39) | FFAR1DGAT1 | |
| SCHEMBL25297920 | 0.78 | FFAR1 (0.58) | FFAR1PDK2DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2569301-A1 | INDAZOLE INHIBITORS OF KINASE | Abbvie Inc. (US) | 2013-03-20 | — | — | EP | disclosed |
| WO-2011143430-A1 | INDAZOLE INHIBITORS OF KINASE | ABBOTT LABORATORIES (US) | 2011-11-17 | — | — | WO | disclosed |