Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 7/20 | 0.79 |
| ▸ | PGR | P06401 | 1/20 | 0.76 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14086875 | 0.89 | AR (0.80) | ARPGRCYP3A4 | |
| SCHEMBL8409323 | 0.89 | AR (0.80) | ARPGRCYP3A4 | |
| SCHEMBL13244698 | 0.89 | AR (0.80) | ARPGRCYP3A4 | |
| SCHEMBL14086873 | 0.89 | AR (0.80) | ARPGRCYP3A4 | |
| SCHEMBL5178725 | 0.88 | AR (0.79) | ARPGRCYP3A4 | |
| SCHEMBL29504174 | 0.88 | AR (1.00) | ARPGRCYP3A4 | |
| SCHEMBL14086878 | 0.88 | AR (0.79) | ARPGRCYP3A4 | |
| SCHEMBL19741507 | 0.88 | AR (1.00) | ARPGRCYP3A4 | |
| SCHEMBL1124550 | 0.88 | AR (1.00) | ARPGRCYP3A4 | |
| SCHEMBL13244539 | 0.87 | AR (0.77) | ARPGRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4806508-B2 | — | — | 2011-11-02 | — | — | JP | claimed |
| WO-2001058855-A9 | USE OF ANDROGEN RECEPTOR SUPPRESSORS | BIOPHYSICA INC (US) | 2002-10-31 | — | — | WO | claimed |
| WO-2001058855-A1 | USE OF ANDROGEN RECEPTOR SUPPRESSORS | BIOPHYSICA, INC (US) | 2001-08-16 | — | — | WO | claimed |
| CN-100402492-C | Androgen receptor suppressors in treatment of hirsutism,acne and androgenetic alopecia | BIOPHYSICA INC (US) | 2008-07-16 | — | — | CN | disclosed |
| EP-1144366-B1 | 3,4-DISUBSTITUTED ACYLANILIDE DERIVATIVES AND THEIR USE AS ANDROGEN RECEPTOR SUPPRESSORS | BIOPHYSICA INC (US) | 2007-06-27 | — | — | EP | disclosed |
| EP-1169301-B1 | A TOPICAL ANTIANDROGEN FOR HAIR LOSS AND OTHER HYPERANDROGENIC CONDITIONS | BIOPHYSICA INC (US) | 2004-02-18 | — | — | EP | disclosed |
| US-6472415-B1 | Androgen receptor suppressors in the therapy and diagnosis of prostate cancer, alopecia and other hyper-androgenic syndromes | BIOPHYSICA, INC. | 2002-10-29 | — | — | US | disclosed |
| EP-1169301-A1 | A TOPICAL ANTIANDROGEN FOR HAIR LOSS AND OTHER HYPERANDROGENIC CONDITIONS | BIOPHYSICA, INC. (US) | 2002-01-09 | — | — | EP | disclosed |
| WO-2001058854-A1 | A TOPICAL ANTIANDROGEN FOR HAIR LOSS AND OTHER HYPERANDROGENIC CONDITIONS | BIOPHYSICA, INC. (US) | 2001-08-16 | — | — | WO | disclosed |
| US-6184249-B1 | Androgen receptor suppressors in the therapy and diagnosis of prostate cancer, alopecia and other hyper-androgenic syndromes | BIOPHYSICA, INC. | 2001-02-06 | — | — | US | disclosed |