Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 9/20 | 1.00 |
| ▸ | PGR | P06401 | 1/20 | 0.76 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19741507 | 1.00 | AR (1.00) | ARPGRCYP3A4 | |
| SCHEMBL1124550 | 1.00 | AR (1.00) | ARPGRCYP3A4 | |
| SCHEMBL14086875 | 0.89 | AR (0.80) | ARPGRCYP3A4 | |
| SCHEMBL13244698 | 0.89 | AR (0.80) | ARPGRCYP3A4 | |
| SCHEMBL8409323 | 0.89 | AR (0.80) | ARPGRCYP3A4 | |
| SCHEMBL14086873 | 0.89 | AR (0.80) | ARPGRCYP3A4 | |
| SCHEMBL14086878 | 0.88 | AR (0.79) | ARPGRCYP3A4 | |
| SCHEMBL5178725 | 0.88 | AR (0.79) | ARPGRCYP3A4 | |
| SCHEMBL2641121 | 0.88 | AR (0.79) | ARPGRCYP3A4 | |
| SCHEMBL14086876 | 0.88 | AR (0.83) | ARPGRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117751099-A | Amide compound and application thereof | 中国药科大学 | 2024-03-22 | — | — | CN | disclosed |
| CN-115701991-A | Pyrazolylpropionamide compounds and their use for treating prostate cancer | 田纳西大学研究基金会 | 2023-02-14 | — | — | CN | disclosed |
| WO-2023011596-A1 | AMIDE COMPOUND AND USE THEREOF | 中国药科大学 | 2023-02-09 | — | — | WO | disclosed |
| EP-4125846-A1 | PYRAZOLYLPROPANAMIDE COMPOUNDS AND USES THEREOF FOR TREATMENT OF PROSTATE CANCER | University of Tennessee Research Foundation (US) | 2023-02-08 | — | — | EP | disclosed |
| EP-4110327-A1 | SELECTIVE ANDROGEN RECEPTOR DEGRADER (SARD) LIGANDS AND METHODS OF USE THEREOF | University of Tennessee Research Foundation (US) | 2023-01-04 | — | — | EP | disclosed |
| EP-3976577-A1 | SELECTIVE ANDROGEN RECEPTOR DEGRADER (SARD) LIGANDS AND METHODS OF USE THEREOF | University of Tennessee Research Foundation (US) | 2022-04-06 | — | — | EP | disclosed |