Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MBOAT4 | Q96T53 | 3/20 | 0.44 |
| ▸ | AR | P10275 | 5/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.34 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2641299 | 0.92 | MBOAT4 (0.41) | MBOAT4ARGRIN1GRIN2BKCNH2 | |
| SCHEMBL4800087 | 0.77 | AR (0.46) | MBOAT4ARSRD5A1SRD5A2 | |
| SCHEMBL10701147 | 0.76 | MBOAT4 (0.44) | MBOAT4ARGRIN1GRIN2BKCNH2 | |
| SCHEMBL4800292 | 0.76 | AR (0.37) | MBOAT4ARGRIN1GRIN2BKCNH2 | |
| SCHEMBL9318312 | 0.76 | MBOAT4 (0.50) | MBOAT4ARGRIN1GRIN2BKCNH2 | |
| SCHEMBL5069359 | 0.69 | MBOAT4 (0.43) | MBOAT4ARKCNH2 | |
| SCHEMBL8158365 | 0.69 | MBOAT4 (0.41) | MBOAT4ARGRIN1GRIN2BKCNH2 | |
| SCHEMBL9113552 | 0.68 | AR (0.64) | ARKCNH2SRD5A2 | |
| SCHEMBL14300609 | 0.68 | AR (0.64) | ARKCNH2SRD5A2 | |
| SCHEMBL9221841 | 0.68 | AR (0.64) | ARKCNH2SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4832303-B2 | — | — | 2011-12-07 | — | — | JP | claimed |
| EP-1622567-A4 | ANDROGEN RECEPTOR MODULATORS AND METHODS OF USE THEREOF | MERCK & CO INC (US) | 2009-04-29 | — | — | EP | claimed |
| EP-1622567-A2 | ANDROGEN RECEPTOR MODULATORS AND METHODS OF USE THEREOF | Merck & Co., Inc. (US) | 2006-02-08 | — | — | EP | claimed |
| WO-2004100874-A2 | ANDROGEN RECEPTOR MODULATORS AND METHODS OF USE THEREOF | MERCK & CO., INC. (US) | 2004-11-25 | — | — | WO | claimed |