Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCEH1 | Q6PIU2 | 6/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3915104 | 0.79 | NCEH1 (0.70) | NCEH1KMT2AMEN1KDM4EHTT | |
| SCHEMBL11807725 | 0.79 | NCEH1 (0.54) | NCEH1KMT2AHPGDCYP1A2MAPT | |
| SCHEMBL5941038 | 0.78 | ALDH1A1 (0.49) | KMT2AMEN1KDM4EGAAALDH1A1 | |
| SCHEMBL31376353 | 0.78 | ALDH1A1 (0.49) | KMT2AMEN1KDM4EGAAALDH1A1 | |
| SCHEMBL24650176 | 0.78 | NCEH1 (0.54) | NCEH1KMT2AMEN1RCE1HPGD | |
| SCHEMBL17502745 | 0.78 | KDM4E (0.53) | NCEH1KMT2AKDM4EALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL28705663 | 0.77 | NCEH1 (0.53) | NCEH1KMT2AMEN1RCE1HPGD | |
| Hydrochloric Acid SCHEMBL28705662 | 0.77 | NCEH1 (0.53) | NCEH1KMT2AMEN1RCE1HPGD | |
| Benzene SCHEMBL27947280 | 0.77 | PPARG (0.50) | KMT2AKDM4EGAAALDH1A1HPGD | |
| SCHEMBL2556427 | 0.77 | MAPT (0.69) | NCEH1KMT2AKDM4EGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2438037-A1 | GLYCINE B ANTAGONISTS | Merz Pharma GmbH & Co. KGaA (DE) | 2012-04-11 | — | — | EP | disclosed |
| WO-2010139481-A1 | GLYCINE B ANTAGONISTS | MERZ PHARMA GMBH & CO. KGAA (DE) | 2010-12-09 | — | — | WO | disclosed |