Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.35 |
| ▸ | PI4KA | P42356 | 1/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 2/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.32 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.32 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.31 |
| ▸ | TIPARP | Q7Z3E1 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26414389 | 0.82 | RECQL (0.33) | PIK3CAPOLBTDP1RECQLLMNA | |
| SCHEMBL23640025 | 0.81 | TSHR (0.46) | TSHRPIK3CAPIK3CDPIK3CBPI4KA | |
| SCHEMBL21585396 | 0.81 | POLB (0.37) | POLBTDP1RECQLLMNAPDE10A | |
| SCHEMBL26087681 | 0.81 | PIK3CA (0.41) | TSHRPIK3CAPIK3CDPIK3CBPI4KA | |
| SCHEMBL15195563 | 0.80 | PPIA (0.32) | POLBTDP1RECQLHTR7 | |
| SCHEMBL13634443 | 0.79 | TSHR (0.38) | TSHRPIK3CAPIK3CDPIK3CBPI4KA | |
| SCHEMBL31587296 | 0.79 | TSHR (0.40) | TSHRPIK3CAPIK3CDPIK3CBPI4KA | |
| SCHEMBL1911864 | 0.78 | POLB (0.52) | TSHRPOLBTDP1RECQLALDH1A1 | |
| SCHEMBL13624091 | 0.78 | TSHR (0.37) | TSHRPIK3CAPIK3CDPIK3CBPI4KA | |
| SCHEMBL16931148 | 0.75 | TSHR (0.44) | TSHRPIK3CAPIK3CDPIK3CBPI4KA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023072962-A1 | SUBSTITUTED QUINOLINES AS IMPROVED NF-KB-INDUCING KINASE (NIK) INHIBITORS | Yukin Therapeutics (FR) | 2023-05-04 | — | — | WO | disclosed |
| EP-4169904-A1 | SUBSTITUTED QUINOLINES AS IMPROVED NF-KB-INDUCING KINASE (NIK) INHIBITORS | Yukin Therapeutics (FR) | 2023-04-26 | — | — | EP | disclosed |