Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | NNMT | P40261 | 1/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 5/20 | 0.41 |
| ▸ | BRD9 | Q9H8M2 | 2/20 | 0.40 |
| ▸ | BRD7 | Q9NPI1 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.37 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | ERN1 | O75460 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21585396 | 0.81 | POLB (0.37) | POLBTDP1RECQLPDE10ASMN1; SMN2 | |
| SCHEMBL31546798 | 0.79 | RECQL (0.36) | POLBTDP1CYP1A2KMT2ARECQL | |
| SCHEMBL18952434 | 0.78 | POLB (0.54) | POLBTDP1CYP1A2KMT2ARECQL | |
| SCHEMBL10075373 | 0.78 | APOBEC3A (0.42) | POLBCYP1A2KMT2ARAB9ANPC1 | |
| SCHEMBL17276010 | 0.78 | BRD9 (0.56) | POLBTDP1CYP1A2KMT2ARECQL | |
| SCHEMBL172558 | 0.78 | NNMT (0.52) | POLBTDP1CYP1A2KMT2ANNMT | |
| SCHEMBL31438401 | 0.78 | BRD9 (0.56) | POLBTDP1CYP1A2KMT2ARECQL | |
| SCHEMBL22621616 | 0.76 | POLB (0.52) | POLBTDP1CYP1A2KMT2ARECQL | |
| SCHEMBL25009545 | 0.76 | POLB (0.37) | POLBTDP1CYP1A2KMT2ARECQL | |
| SCHEMBL22198926 | 0.76 | HAO1 (0.44) | POLBKMT2ATSHRMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 251 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11771738-B2 | Endoparasitic depsipeptides | ZOETIS SERVICES LLC (US) | 2023-10-03 | — | — | US | disclosed |
| US-11771738-B2 | Endoparasitic depsipeptides | ZOETIS SERVICES LLC (US) | 2023-10-03 | — | — | US | disclosed |
| US-20230303611-A1 | SYNTHESIS OF AN ANTIVIRAL AZASUGAR TRIPHOSPHATE | WILMINGTON TRUST, NATIONAL ASSOCIATION | 2023-09-28 | — | — | US | disclosed |
| US-20230303611-A1 | SYNTHESIS OF AN ANTIVIRAL AZASUGAR TRIPHOSPHATE | WILMINGTON TRUST, NATIONAL ASSOCIATION | 2023-09-28 | — | — | US | disclosed |
| WO-2023014908-A1 | LPAR1 ANTAGONISTS AND USES THEREOF | Pipeline Therapeutics, Inc. (US) | 2023-02-09 | — | — | WO | disclosed |
| EP-3802517-B1 | ALKOXY-SUBSTITUTED PYRIDINYL DERIVATIVES AS LPA1 RECEPTOR ANTAGONISTS AND THEIR USE IN THE TREATMENT OF FIBROSIS | IDORSIA PHARMACEUTICALS LTD (CH) | 2022-12-21 | — | — | EP | disclosed |
| US-11530175-B2 | Method for preparation of fluoro alkylated compounds by homogeneous Ni catalysis | ARXADA AG (CH) | 2022-12-20 | — | — | US | disclosed |
| US-20220041530-A1 | Method for Preparation of Fluoro Alkylated Compounds by Homogeneous NI Catalysis | LONZA LTD (CH) | 2022-02-10 | — | — | US | disclosed |
| WO-2021183762-A1 | IMMUNOMODULATING O-HET-ARYL AZALIDES | ZOETIS SERVICES LLC (US) | 2021-09-16 | — | — | WO | disclosed |
| US-20210246116-A1 | ALKOXY-SUBSTITUTED PYRIDINYL DERIVATIVES AS LPA1 RECEPTOR ANTAGONISTS AND THEIR USE IN THE TREATMENT OF FIBROSIS | IDORSIA PHARMACEUTICALS LTD (CH) | 2021-08-12 | — | — | US | disclosed |
| US-7169789-B2 | Quinoline derivatives and quinazoline derivatives | KIRIN BEER KABUSHIKI KAISHA (JP) | 2007-01-30 | — | — | US | disclosed |
| US-7169789-B2 | Quinoline derivatives and quinazoline derivatives | KIRIN BEER KABUSHIKI KAISHA (JP) | 2007-01-30 | — | — | US | disclosed |
| US-7160900-B2 | Tetrahydropyridino or piperidino heterocyclic derivatives | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2007-01-09 | — | — | US | disclosed |
| WO-2006070192-A1 | THIAZOLE AND ISOTHIAZOLE DERIVATIVES THAT MODULATE THE ACIVITY OF CDK, GSK AND AURORA KYNASES | ASTEX THERAPEUTICS LIMITED (GB) | 2006-07-06 | — | — | WO | disclosed |
| WO-2005007621-A2 | UBIQUITIN LIGASE INHIBITORS | RIGEL PHARMACEUTICALS, INC. (US) | 2005-01-27 | — | — | WO | disclosed |
| WO-2005002552-A2 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS PROTEIN KINASES INHIBITORS | ASTEX THERAPEUTICS LIMITED (GB) | 2005-01-13 | — | — | WO | disclosed |
| US-5157018-A | Phenolic resins; for waterless offset printing plates | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-10-20 | — | — | US | disclosed |
| US-5104961-A | Waterless offset printing | HOECHST CELANESE CORPORATION (US) | 1992-04-14 | — | — | US | disclosed |
| US-5006443-A | Radiation sensitive reproduction composition and element with perfluoroalkyl group containing polymer | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-04-09 | — | — | US | disclosed |
| EP-0164059-A2 | Polymers having perfluoroalkyl groups, reproducing layers containing them, and their use in non-aqueous offset printing | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-12-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220041530-A1 | Method for Preparation of Fluoro Alkylated Compounds by Homogeneous NI Catalysis | ABL1, AFF2, NAF1 | POLB 838/4885TDP1 2062/4885CYP1A2 172/4885 |
| US-11530175-B2 | Method for preparation of fluoro alkylated compounds by homogeneous Ni catalysis | ABL1, AFF2, NAF1 | POLB 838/4885TDP1 2062/4885CYP1A2 172/4885 |
| US-11771738-B2 | Endoparasitic depsipeptides | VIP, PREP, VIPR1 | POLB 4515/4885TDP1 3426/4885CYP1A2 1888/4885 |
| US-20210246116-A1 | ALKOXY-SUBSTITUTED PYRIDINYL DERIVATIVES AS LPA1 RECEPTOR ANTAGONISTS AND THEIR USE IN THE TREATMENT OF FIBROSIS | LPAR1, LPAR3, LPAR2 | POLB 3402/4885TDP1 3521/4885CYP1A2 899/4885 |
| US-20230303611-A1 | SYNTHESIS OF AN ANTIVIRAL AZASUGAR TRIPHOSPHATE | RNGTT, ADAR, MTAP | POLB 152/4885TDP1 947/4885CYP1A2 1893/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.