⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26414862 | 0.84 | — | — | |
| SCHEMBL19922747 | 0.83 | EPHB4 (0.30) | — | |
| SCHEMBL19922748 | 0.81 | PARP1 (0.33) | — | |
| SCHEMBL19922749 | 0.80 | EPHB4 (0.37) | — | |
| SCHEMBL19922742 | 0.80 | EPHB4 (0.35) | — | |
| SCHEMBL30450190 | 0.80 | EPHB4 (0.35) | — | |
| SCHEMBL19922726 | 0.80 | EPHB4 (0.32) | — | |
| Zagociguat SCHEMBL19922804 | 0.79 | AR (0.34) | — | |
| SCHEMBL19922759 | 0.78 | EPHB4 (0.32) | — | |
| Zagociguat SCHEMBL21332996 | 0.78 | AR (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230130739-A1 | DEUTERATED sGC STIMULATORS | TISENTO THERAPEUTICS INC. | 2023-04-27 | — | — | US | disclosed |