Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK7 | P49862 | 2/20 | 0.60 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.55 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.53 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.53 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28589406 | 1.00 | KLK7 (0.60) | KLK7KLK5MAPTITGB3ITGA2B | |
| SCHEMBL2291347 | 1.00 | KLK7 (0.60) | KLK7KLK5MAPTITGB3ITGA2B | |
| SCHEMBL19499042 | 0.99 | KLK7 (0.59) | KLK7KLK5MAPTITGB3ITGA2B | |
| SCHEMBL16920618 | 0.99 | KLK7 (0.59) | KLK7KLK5MAPTITGB3ITGA2B | |
| SCHEMBL30668140 | 0.96 | KLK7 (0.57) | KLK7KLK5MAPTITGB3ITGA2B | |
| SCHEMBL7549143 | 0.96 | KLK7 (0.64) | KLK7KLK5MAPTITGB3ITGA2B | |
| SCHEMBL12890795 | 0.93 | CTSK (0.60) | KLK7KLK5MAPTITGB3ITGA2B | |
| SCHEMBL30544856 | 0.93 | KLK7 (0.63) | KLK7KLK5MAPTITGB3ITGA2B | |
| SCHEMBL27497192 | 0.93 | KLK7 (0.63) | KLK7KLK5MAPTITGB3ITGA2B | |
| SCHEMBL9875747 | 0.92 | MAPT (0.61) | KLK7KLK5MAPTITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107709342-A | Process for preparing acetylgalactosamine acid derivatives | 豪夫迈·罗氏有限公司 | 2018-02-16 | — | — | CN | disclosed |