Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29471378 | 0.78 | TAAR1 (0.41) | TDP1TAAR1 | |
| SCHEMBL2339012 | 0.78 | TAAR1 (0.41) | TDP1TAAR1 | |
| SCHEMBL30444664 | 0.78 | TDP1 (0.44) | TDP1TAAR1 | |
| SCHEMBL337883 | 0.78 | TDP1 (0.44) | TDP1TAAR1 | |
| SCHEMBL29774984 | 0.76 | AKR1B1 (0.40) | — | |
| SCHEMBL19442878 | 0.76 | — | — | |
| SCHEMBL23694192 | 0.75 | TAAR1 (0.39) | TAAR1 | |
| SCHEMBL1560222 | 0.75 | TAAR1 (0.38) | TDP1TAAR1 | |
| SCHEMBL29471364 | 0.75 | TAAR1 (0.39) | TAAR1 | |
| SCHEMBL16958402 | 0.75 | TAAR1 (0.38) | TDP1TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2643310-A1 | 4- (5-CYANO-PYRAZOL-1-YL) -PIPERIDINE DERIVATIVES AS GPR 119 MODULATORS | Pfizer Inc (US) | 2013-10-02 | — | — | EP | disclosed |
| WO-2012069948-A1 | 4- (5-CYANO-PYRAZOL-1-YL) -PIPERIDINE DERIVATIVES AS GPR 119 MODULATORS | PFIZER INC. (US) | 2012-05-31 | — | — | WO | disclosed |
| EP-2438051-A1 | L- ( PIPERIDIN-4-YL) -PYRAZOLE DERIVATIVES AS GPR 119 MODULATORS | Pfizer Inc. (US) | 2012-04-11 | — | — | EP | disclosed |
| WO-2010140092-A1 | L- ( PIPERIDIN-4-YL) -PYRAZOLE DERIVATIVES AS GPR 119 MODULATORS | PFIZER INC. (US) | 2010-12-09 | — | — | WO | disclosed |