Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.34 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | MDM4 | O15151 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30444664 | 1.00 | TDP1 (0.44) | TDP1PTPN1MAPTHDAC8APOBEC3G | |
| SCHEMBL10682655 | 0.86 | POLB (0.38) | TDP1MAPTHDAC8APOBEC3GCA2 | |
| SCHEMBL5174795 | 0.84 | IDO1 (0.36) | MAPTHDAC8FOLH1TAAR1HSPA5 | |
| SCHEMBL29534868 | 0.81 | TDP1 (0.55) | TDP1PTPN1APOBEC3GTAAR1HSPA5 | |
| SCHEMBL31203 | 0.81 | TDP1 (0.55) | TDP1PTPN1APOBEC3GTAAR1HSPA5 | |
| SCHEMBL27952236 | 0.79 | LIPG (0.34) | MAPTHDAC8FOLH1TAAR1IDO1 | |
| SCHEMBL423675 | 0.79 | — | — | |
| SCHEMBL2641641 | 0.78 | TDP1 (0.33) | TDP1TAAR1 | |
| SCHEMBL27985437 | 0.77 | FOLH1 (0.48) | FOLH1TAAR1IDO1 | |
| SCHEMBL27457207 | 0.77 | APOBEC3G (0.46) | TDP1MAPTHDAC8APOBEC3GHSPA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4122258-A | Process for producing desacetoxycephalosporin derivatives by heating a penicillin-1-oxide in presence of an organic sulfide | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1978-10-24 | — | — | US | claimed |
| CN-110944629-B | Enzyme-triggered carbon monoxide release molecules | 乔治亚州立大学研究基金会股份有限公司 | 2024-04-09 | — | — | CN | disclosed |
| EP-3638222-B1 | ENZYME-TRIGGERED CARBON MONOXIDE RELEASING MOLECULES | UNIV GEORGIA STATE RES FOUND (US) | 2024-04-03 | — | — | EP | disclosed |
| CN-111393683-B | Modified cationic microgel and preparation method and application thereof | 广东科德环保科技股份有限公司 | 2023-05-23 | — | — | CN | disclosed |
| US-11377435-B2 | Enzyme-triggered carbon monoxide releasing molecules | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2022-07-05 | — | — | US | disclosed |
| US-20200392498-A1 | POLYNUCLEOTIDE CONSTRUCTS HAVING BIOREVERSIBLE AND NON-BIOREVERSIBLE GROUPS | SOLSTICE BIOLOGICS LTD (IE) | 2020-12-17 | — | — | US | disclosed |
| WO-2020155595-A1 | AEROBIC OXIDATION SYSTEM CONTAINING SULFINIC ACID, SULFONIC ACID OR DERIVATIVES THEREOF AND PHOTOCATALYTIC OXIDATION METHOD THEREFOR | 清华大学 | 2020-08-06 | — | — | WO | disclosed |
| EP-3638222-A1 | ENZYME-TRIGGERED CARBON MONOXIDE RELEASING MOLECULES | Georgia State University Research Foundation, Inc. (US) | 2020-04-22 | — | — | EP | disclosed |
| US-20200115360-A1 | ENZYME-TRIGGERED CARBON MONOXIDE RELEASING MOLECULES | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC, | 2020-04-16 | — | — | US | disclosed |
| CN-110944629-A | Enzyme-triggered carbon monoxide releasing molecules | 乔治亚州立大学研究基金会股份有限公司 | 2020-03-31 | — | — | CN | disclosed |
| WO-2002100860-A2 | HETEROCYCLIC COMPOUNDS, METHOD FOR PREPARING SAME AND USE THEREOF AS MEDICINES, IN PARTICULAR AS ANTI-BACTERIAL AGENTS | AVENTIS PHARMA S.A. (FR) | 2002-12-19 | — | — | WO | disclosed |
| EP-0822936-A1 | NOVEL SUBSTITUTED TETRAHYDROPYRANO 3,2-d]OXAZOLONES, METHOD FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ADIR ET COMPAGNIE (FR) | 1998-02-11 | — | — | EP | disclosed |
| WO-1996033999-A1 | NOVEL SUBSTITUTED TETRAHYDROPYRANO[3,2-d]OXAZOLONES, METHOD FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ADIR ET COMPAGNIE (FR) | 1996-10-31 | — | — | WO | disclosed |
| US-5177211-A | Anti-platelet aggregation and anti-hypotensive | ALTER, S.A. (ES) | 1993-01-05 | — | — | US | disclosed |
| EP-0325187-B1 | 4-ALKYL-1, 4-DIHYDROPYRIDINES WITH PAF-ANTAGONIST ACTIVITY | ALTER, S.A. (ES) | 1992-11-11 | — | — | EP | disclosed |
| EP-0325187-A1 | 4-alkyl-1, 4-dihydropyridines with PAF-antagonist activity | ALTER, S.A. (ES) | 1989-07-26 | — | — | EP | disclosed |
| EP-0060799-B1 | DIESTER ANTIOXIDANTS | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1984-06-06 | — | — | EP | disclosed |
| US-4246267-A | HYPOTENSIVE AGENTS | SCIENCE UNION ET CIE (FR) | 1981-01-20 | — | — | US | disclosed |
| US-4122258-A | Process for producing desacetoxycephalosporin derivatives by heating a penicillin-1-oxide in presence of an organic sulfide | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1978-10-24 | — | — | US | disclosed |
| US-4108831-A | FOR CONJUGATED DIENE POLYMERS | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1978-08-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11377435-B2 | Enzyme-triggered carbon monoxide releasing molecules | CNDP2, CPN1, JMJD7 | TDP1 973/4885PTPN1 3711/4885MAPT 4628/4885 |
| US-20200392498-A1 | POLYNUCLEOTIDE CONSTRUCTS HAVING BIOREVERSIBLE AND NON-BIOREVERSIBLE GROUPS | HNRNPC, RNASE1, NSUN3 | TDP1 495/4885PTPN1 1980/4885MAPT 4716/4885 |
| US-20200115360-A1 | ENZYME-TRIGGERED CARBON MONOXIDE RELEASING MOLECULES | CNDP2, CPN1, JMJD7 | TDP1 1043/4885PTPN1 3731/4885MAPT 4628/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.