SCHEMBL26416508

SCHEMBL26416508

c1ccc(-c2ccc(N(c3ccccc3)c3ccc(-c4ccc5c(c4)oc4c(-c6nc(-c7ccccc7)c7sc8ccccc8c7n6)cccc45)cc3)cc2)cc1

nearest known ligand 0.34

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PRKDC P78527 2/20 0.34
LIMK1 P53667 2/20 0.32
ESR2 Q92731 1/20 0.31
ALOX5 P09917 1/20 0.31
PIM1 P11309 1/20 0.31
PIM3 Q86V86 1/20 0.31
PIM2 Q9P1W9 1/20 0.31
APP P05067 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22195501 0.91 PRKDC (0.36) PRKDCLIMK1ESR2ALOX5PIM1
SCHEMBL22195838 0.91 PRKDC (0.36) PRKDCLIMK1ESR2ALOX5PIM1
SCHEMBL22195443 0.91 PRKDC (0.36) PRKDCLIMK1ESR2ALOX5PIM1
SCHEMBL22195582 0.89 PRKDC (0.35) PRKDCLIMK1ESR2ALOX5PIM1
SCHEMBL22195583 0.89 PRKDC (0.35) PRKDCLIMK1ESR2ALOX5PIM1
SCHEMBL22196113 0.89 PRKDC (0.36) PRKDCLIMK1ESR2ALOX5
SCHEMBL22329444 0.89 PRKDC (0.36) PRKDCLIMK1ESR2ALOX5
SCHEMBL22196110 0.89 PRKDC (0.36) PRKDCLIMK1ESR2ALOX5
SCHEMBL22195740 0.88 PRKDC (0.35) PRKDCLIMK1ESR2ALOX5
SCHEMBL22195811 0.88 PRKDC (0.36) PRKDCESR2ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230128360-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME, COMPOSITION FOR ORGANIC LAYER OF ORGANIC LIGHT EMITTING DEVICE LT MATERIALS CO., LTD. (KR) 2023-04-27 US disclosed
US-20230128360-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME, COMPOSITION FOR ORGANIC LAYER OF ORGANIC LIGHT EMITTING DEVICE LT MATERIALS CO., LTD. (KR) 2023-04-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230128360-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME, COMPOSITION FOR ORGANIC LAYER OF ORGANIC LIGHT EMITTING DEVICE CRY1, ORC3, ODC1 PRKDC 4741/4885LIMK1 244/4885ESR2 1164/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.