SCHEMBL26416629

SCHEMBL26416629

Nc1ccc(NC(=O)c2c(F)c(F)c(C(=O)Nc3ccc(N)cc3C(F)(F)F)c(F)c2F)c(C(F)(F)F)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 3/20 0.48
CYP1A2 P05177 1/20 0.48
CYP2D6 P10635 1/20 0.48
CYP2C19 P33261 1/20 0.48
HTT P42858 2/20 0.47
TP53 P04637 2/20 0.47
LMNA P02545 1/20 0.47
MAPK1 P28482 1/20 0.47
CA1 P00915 8/20 0.47
CA2 P00918 8/20 0.47
KDM4E B2RXH2 1/20 0.44
GLA P06280 1/20 0.43
POLB P06746 1/20 0.43
GAA P10253 1/20 0.43
TSHR P16473 1/20 0.43
CA9 Q16790 3/20 0.42
KDM4C Q9H3R0 1/20 0.42
PTGS1 P23219 1/20 0.42
MAPT P10636 2/20 0.41
SMN1; SMN2 Q16637 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26416457 0.92 CYP1A2 (0.52) RAB9ACYP1A2CYP2D6CYP2C19HTT
SCHEMBL29996855 0.84 CYP1A2 (0.66) RAB9ACYP1A2CYP2D6CYP2C19LMNA
SCHEMBL26416602 0.84 CYP1A2 (0.66) RAB9ACYP1A2CYP2D6CYP2C19LMNA
SCHEMBL30279461 0.83 PTGS1 (0.52) RAB9ACYP1A2CYP2D6CYP2C19TP53
SCHEMBL21391974 0.83 PTGS1 (0.52) RAB9ACYP1A2CYP2D6CYP2C19TP53
SCHEMBL14972697 0.83 CYP1A2 (0.64) RAB9ACYP1A2CYP2D6CYP2C19LMNA
SCHEMBL4957900 0.81 POLB (0.48) RAB9ACYP1A2CYP2D6CYP2C19HTT
SCHEMBL26416451 0.81 CA1 (0.61) CYP1A2CYP2C19HTTTP53LMNA
SCHEMBL3528827 0.81 MAPT (0.62) RAB9ACYP1A2CYP2D6CYP2C19LMNA
SCHEMBL6814891 0.80 KDM4E (0.55) RAB9AHTTTP53LMNAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230125363-A1 Polyamideimide Precursor, Polyamideimide Prepared Therefrom, and Polyamideimide Film Including the Same SK IE TECHNOLOGY CO., LTD. (KR) 2023-04-27 US disclosed