SCHEMBL26416451

SCHEMBL26416451

Nc1ccc(NC(=O)c2c(F)c(F)c(C(=O)Nc3ccc(N)cc3F)c(F)c2F)c(F)c1

nearest known ligand 0.61

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CA1 P00915 9/20 0.61
CA2 P00918 9/20 0.61
CA9 Q16790 4/20 0.56
HTT P42858 2/20 0.53
MAPK1 P28482 2/20 0.53
LMNA P02545 1/20 0.53
TP53 P04637 1/20 0.53
KDM4C Q9H3R0 1/20 0.46
HDAC1 Q13547 2/20 0.45
MAPT P10636 3/20 0.44
GAA P10253 2/20 0.44
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
XDH P47989 1/20 0.43
SLC22A12 Q96S37 1/20 0.43
CYP1A2 P05177 1/20 0.43
CYP2C9 P11712 1/20 0.43
CYP2C19 P33261 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29996129 0.84 HDAC1 (0.63) MAPK1LMNAHDAC1MAPTGAA
SCHEMBL26416452 0.84 HDAC1 (0.63) MAPK1LMNAHDAC1MAPTGAA
SCHEMBL25394327 0.83 HDAC1 (0.52) CA1CA2MAPK1HDAC1MAPT
SCHEMBL26416629 0.81 RAB9A (0.48) CA1CA2CA9HTTMAPK1
SCHEMBL20577768 0.80 MAPT (0.46) CA1CA2CA9HTTMAPK1
SCHEMBL1161226 0.80 RAB9A (0.48) CA1CA2HTTMAPTMEN1
SCHEMBL28440005 0.79 HDAC1 (0.56) MAPK1LMNAHDAC1MAPTGAA
SCHEMBL30725839 0.79 CA1 (0.61) CA1CA2CA9HTTMAPK1
SCHEMBL116618 0.79 CA1 (0.61) CA1CA2CA9HTTMAPK1
SCHEMBL25393473 0.78 HDAC1 (0.59) MAPK1HDAC1MAPTGAAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230125363-A1 Polyamideimide Precursor, Polyamideimide Prepared Therefrom, and Polyamideimide Film Including the Same SK IE TECHNOLOGY CO., LTD. (KR) 2023-04-27 US disclosed
US-20230125363-A1 Polyamideimide Precursor, Polyamideimide Prepared Therefrom, and Polyamideimide Film Including the Same SK IE TECHNOLOGY CO., LTD. (KR) 2023-04-27 US disclosed