Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | CASP1 | P29466 | 2/20 | 0.55 |
| ▸ | HBB | P68871 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | RELA | Q04206 | 1/20 | 0.53 |
| ▸ | APP | P05067 | 9/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ALPG | P10696 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2641782 | 1.00 | MAPT (0.55) | MAPTMEN1KMT2ACASP1HBB | |
| SCHEMBL2641829 | 0.81 | APP (0.40) | MAPTMEN1KMT2ACASP1HBB | |
| SCHEMBL2641845 | 0.79 | APP (0.61) | MAPTMEN1KMT2ACASP1HBB | |
| SCHEMBL2373640 | 0.79 | MAPT (0.55) | MAPTMEN1KMT2ACASP1HBB | |
| SCHEMBL2641839 | 0.79 | APP (0.61) | MAPTMEN1KMT2ACASP1HBB | |
| SCHEMBL2641766 | 0.79 | APP (0.61) | MAPTMEN1KMT2ACASP1HBB | |
| SCHEMBL2641773 | 0.79 | APP (0.61) | MAPTMEN1KMT2ACASP1HBB | |
| SCHEMBL2373637 | 0.79 | MAPT (0.55) | MAPTMEN1KMT2ACASP1HBB | |
| SCHEMBL2100924 | 0.78 | ALDH1A1 (0.46) | MAPTSMN1; SMN2ALOX15APPALDH1A1 | |
| SCHEMBL31563753 | 0.78 | ALDH1A1 (0.46) | MAPTSMN1; SMN2ALOX15APPALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011141515-A1 | DIAGNOSTIC AGENTS FOR AMYLOID BETA IMAGING | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2011-11-17 | — | — | WO | claimed |
| WO-2011141515-A1 | DIAGNOSTIC AGENTS FOR AMYLOID BETA IMAGING | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2011-11-17 | — | — | WO | disclosed |