SCHEMBL26418223

SCHEMBL26418223

CC(C)OC(=O)C1=CCCCC1S(=O)(=O)Nc1ccc(COC(=O)C(C)C)cc1F

nearest known ligand 0.59

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TLR4 O00206 6/20 0.59
TRPV1 Q8NER1 7/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24668088 0.93 TLR4 (0.59) TLR4TRPV1
SCHEMBL26422869 0.93 TLR4 (0.61) TLR4TRPV1
SCHEMBL26418227 0.90 TLR4 (0.49) TLR4
SCHEMBL26418211 0.87 TLR4 (0.56) TLR4TRPV1
SCHEMBL24668068 0.86 TLR4 (0.56) TLR4TRPV1
SCHEMBL26446125 0.85 TLR4 (0.44) TLR4
SCHEMBL871909 0.85 TLR4 (0.61) TLR4
SCHEMBL23417719 0.84 TLR4 (0.62) TLR4TRPV1
SCHEMBL23417790 0.83 TLR4 (0.49) TLR4
SCHEMBL26422997 0.82 TLR4 (0.51) TLR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240238436-A1 COMPOSITIONS INCLUDING CONJUGATED THERAPY ENHANCERS BIOHAVEN THERAPEUTICS LTD. (VG) 2024-07-18 US disclosed
US-20230128688-A1 DIRECTED CONJUGATION TECHNOLOGIES KLEO PHARMACEUTICALS, INC. 2023-04-27 US disclosed
US-20230128688-A1 DIRECTED CONJUGATION TECHNOLOGIES KLEO PHARMACEUTICALS, INC. 2023-04-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230128688-A1 DIRECTED CONJUGATION TECHNOLOGIES CD2BP2, CD2, CD47 TLR4 3806/4885TRPV1 4868/4885
US-20240238436-A1 COMPOSITIONS INCLUDING CONJUGATED THERAPY ENHANCERS LGMN, LPXN, LY96 TLR4 289/4885TRPV1 4734/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.