Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | CA12 | O43570 | 5/20 | 0.38 |
| ▸ | CA2 | P00918 | 5/20 | 0.38 |
| ▸ | CA1 | P00915 | 4/20 | 0.38 |
| ▸ | CA9 | Q16790 | 4/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20494732 | 0.84 | TDP1 (0.47) | THRBTSHRCA12CA2CA1 | |
| SCHEMBL262736 | 0.84 | TDP1 (0.47) | THRBTSHRCA12CA2CA1 | |
| SCHEMBL262734 | 0.84 | IDO1 (0.40) | THRBTSHRCA12CA2CA1 | |
| SCHEMBL13587939 | 0.83 | THRB (0.51) | THRBTSHRCA12CA2CA1 | |
| SCHEMBL12151441 | 0.83 | THRB (0.51) | THRBTSHRCA12CA2CA1 | |
| SCHEMBL3906055 | 0.83 | THRB (0.51) | THRBTSHRCA12CA2CA1 | |
| SCHEMBL31341432 | 0.81 | CA12 (0.55) | THRBTSHRCA12CA2CA1 | |
| SCHEMBL15128194 | 0.79 | THRB (0.54) | THRBTSHRALDH1A1GAA | |
| SCHEMBL18360370 | 0.79 | TDP1 (0.46) | CA12CA2CA1CA9TDP1 | |
| SCHEMBL22829704 | 0.79 | CA12 (0.62) | TSHRCA12CA2CA1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2443485-B1 | BIOMEDICAL DEVICES | BAUSCH & LOMB (US) | 2017-11-08 | — | — | EP | disclosed |
| EP-2443486-B1 | BIOMEDICAL DEVICES | BAUSCH & LOMB (US) | 2017-03-01 | — | — | EP | disclosed |
| EP-2443482-B1 | BIOMEDICAL DEVICES, POLYMERIC MATERIALS AND CONTACT LENSES COMPRISING THE SAME. | BAUSCH & LOMB (US) | 2017-03-01 | — | — | EP | disclosed |
| EP-2443483-B1 | MULTI-ARMED MACROMONOMERS, POLYMERIC MATERIALS AND CONTACT LENSES COMPRISING SAME. | BAUSCH & LOMB (US) | 2016-03-23 | — | — | EP | disclosed |
| US-9285508-B2 | Biomedical devices | BAUSCH & LOMB INCORPORATED (US) | 2016-03-15 | — | — | US | disclosed |
| EP-2443485-A2 | BIOMEDICAL DEVICES | Bausch & Lomb Incorporated (US) | 2012-04-25 | — | — | EP | disclosed |
| EP-2443482-A2 | BIOMEDICAL DEVICES | Bausch & Lomb Incorporated (US) | 2012-04-25 | — | — | EP | disclosed |
| EP-2443483-A1 | MULTI-ARMED MACROMONOMERS, POLYMERIC MATERIALS AND CONTACT LENSES COMPRISING SAME | Bausch & Lomb Incorporated (US) | 2012-04-25 | — | — | EP | disclosed |
| EP-2443486-A2 | BIOMEDICAL DEVICES | Bausch & Lomb Incorporated (US) | 2012-04-25 | — | — | EP | disclosed |
| US-8133960-B2 | Biomedical devices | BAUSCH & LOMB INCORPORATED (US) | 2012-03-13 | — | — | US | disclosed |
| US-8083348-B2 | Biomedical devices | BAUSCH & LOMB INCORPORATED (US) | 2011-12-27 | — | — | US | disclosed |
| WO-2010147875-A2 | BIOMEDICAL DEVICES | BAUSCH & LOMB INCORPORATED (US) | 2010-12-23 | — | — | WO | disclosed |
| WO-2010147865-A1 | MULTI-ARMED MACROMONOMERS, POLYMERIC MATERIALS AND CONTACT LENSES COMPRISING SAME | BAUSCH & LOMB INCORPORATED (US) | 2010-12-23 | — | — | WO | disclosed |
| WO-2010147864-A2 | BIOMEDICAL DEVICES | BAUSCH & LOMB INCORPORATED (US) | 2010-12-23 | — | — | WO | disclosed |
| WO-2010147876-A2 | BIOMEDICAL DEVICES | BAUSCH & LOMB INCORPORATED (US) | 2010-12-23 | — | — | WO | disclosed |
| US-20100317816-A1 | Biomedical devices | BAUSCH & LOMB INCORPORATED (US) | 2010-12-16 | — | — | US | disclosed |
| US-20100318185-A1 | Biomedical Devices | BAUSCH & LOMB INCORPORATED (US) | 2010-12-16 | — | — | US | disclosed |
| US-20100317817-A1 | Biomedical devices | BAUSCH & LOMB INCORPORATED (US) | 2010-12-16 | — | — | US | disclosed |
| US-20100315588-A1 | Biomedical devices | BAUSCH & LOMB INCORPORATED (US) | 2010-12-16 | — | — | US | disclosed |