Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 11/20 | 0.60 |
| ▸ | HDAC6 | Q9UBN7 | 10/20 | 0.60 |
| ▸ | KDM1A | O60341 | 6/20 | 0.60 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 3/20 | 0.39 |
| ▸ | MMP2 | P08253 | 3/20 | 0.39 |
| ▸ | MMP9 | P14780 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2641864 | 1.00 | HDAC1 (0.60) | HDAC1HDAC6KDM1AHDAC3HDAC8 | |
| SCHEMBL2641912 | 0.84 | ALDH1A1 (0.45) | HDAC1HDAC6KDM1AHDAC3HDAC8 | |
| SCHEMBL2641767 | 0.84 | KDM4E (0.41) | HDAC1HDAC6KDM1AHDAC3HDAC8 | |
| SCHEMBL2641909 | 0.84 | ALDH1A1 (0.45) | HDAC1HDAC6KDM1AHDAC3HDAC8 | |
| SCHEMBL2641809 | 0.84 | KDM4E (0.41) | HDAC1HDAC6KDM1AHDAC3HDAC8 | |
| SCHEMBL2641814 | 0.84 | KDM4E (0.41) | HDAC1HDAC6KDM1AHDAC3HDAC8 | |
| SCHEMBL2641775 | 0.84 | KDM4E (0.41) | HDAC1HDAC6KDM1AHDAC3HDAC8 | |
| SCHEMBL2641827 | 0.82 | HDAC1 (0.44) | HDAC1HDAC6KDM1AHDAC3HDAC8 | |
| SCHEMBL2641833 | 0.82 | HDAC1 (0.44) | HDAC1HDAC6KDM1AHDAC3HDAC8 | |
| SCHEMBL2641866 | 0.80 | ALDH1A1 (0.42) | HDAC1HDAC6KDM1AHDAC3HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011141515-A1 | DIAGNOSTIC AGENTS FOR AMYLOID BETA IMAGING | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2011-11-17 | — | — | WO | claimed |
| WO-2011141515-A1 | DIAGNOSTIC AGENTS FOR AMYLOID BETA IMAGING | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2011-11-17 | — | — | WO | disclosed |