Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.49 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.44 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.44 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.36 |
| ▸ | MOGAT2 | Q3SYC2 | 1/20 | 0.36 |
| ▸ | OGA | O60502 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | BTK | Q06187 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21140748 | 0.94 | HRH3 (0.45) | HRH3TLR7ASIC3TMEM97SIGMAR1 | |
| SCHEMBL14084766 | 0.86 | TMEM97 (0.45) | TMEM97SIGMAR1KCNH2NPC1RAB9A | |
| SCHEMBL21485543 | 0.86 | HRH3 (0.48) | HRH3TLR7ASIC3TMEM97SIGMAR1 | |
| SCHEMBL21462204 | 0.86 | HRH3 (0.48) | HRH3TLR7ASIC3TMEM97SIGMAR1 | |
| Hydrochloric Acid SCHEMBL21465867 | 0.84 | HRH3 (0.47) | HRH3TLR7ASIC3TMEM97SIGMAR1 | |
| SCHEMBL25091108 | 0.81 | MOGAT2 (0.43) | HRH3TLR7ASIC3TMEM97SIGMAR1 | |
| SCHEMBL24732571 | 0.80 | KMT2A (0.57) | HRH3TLR7ASIC3TMEM97SIGMAR1 | |
| SCHEMBL10066156 | 0.80 | MAOA (0.52) | HRH3TLR7 | |
| SCHEMBL23032967 | 0.79 | HRH3 (0.44) | HRH3TLR7ASIC3TMEM97SIGMAR1 | |
| SCHEMBL28641279 | 0.79 | HRH3 (0.44) | HRH3TLR7ASIC3TMEM97SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4169919-A1 | PYRAZOLO[3,4-D]PYRIMIDINE-3-KETONE DERIVATIVE AS WEE-1 INHIBITOR | Wigen Biomedicine Technology (Shanghai) Co., Ltd. (CN) | 2023-04-26 | — | — | EP | disclosed |