SCHEMBL26418991

SCHEMBL26418991

COC(O)C(C)n1cc(/C=C2\C(=O)N(c3ccc(O)cc3)N(c3ccc(C(=O)O)cc3)C2=O)c2ccccc21

nearest known ligand 0.43

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 13/20 0.43
▸ MEN1 O00255 12/20 0.43
▸ GAA P10253 1/20 0.43
▸ GFER P55789 1/20 0.43
▸ MAPT P10636 3/20 0.37
▸ MAPK1 P28482 2/20 0.37
▸ NPC1 O15118 1/20 0.37
▸ RAB9A P51151 1/20 0.37
▸ DHFR P00374 3/20 0.37
▸ CRHBP P24387 3/20 0.35
▸ CRHR2 Q13324 3/20 0.35
▸ KDM4E B2RXH2 1/20 0.35
▸ L3MBTL1 Q9Y468 2/20 0.35
▸ ALDH1A1 P00352 2/20 0.35
▸ POLB P06746 1/20 0.35
▸ NPSR1 Q6W5P4 1/20 0.34
▸ THRB P10828 1/20 0.34
▸ USP2 O75604 1/20 0.34
▸ LMNA P02545 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26418970 0.86 KMT2A (0.46) KMT2AMEN1GAAGFERMAPT
SCHEMBL22924032 0.86 KMT2A (0.46) KMT2AMEN1GAAGFERMAPT
SCHEMBL24614118 0.78 KMT2A (0.46) KMT2AMEN1GAAGFERMAPT
SCHEMBL22924019 0.76 KMT2A (0.44) KMT2AMEN1GAAGFERMAPT
SCHEMBL24251265 0.75 MEN1 (0.45) KMT2AMEN1GAAGFERMAPT
SCHEMBL26277374 0.74 KMT2A (0.38) KMT2AMEN1GAAGFERMAPT
SCHEMBL26277375 0.70 MEN1 (0.45) KMT2AMEN1GAAGFERMAPT
SCHEMBL24943513 0.70 MEN1 (0.45) KMT2AMEN1GAAGFERMAPT
SCHEMBL12126397 0.69 KAT8 (0.56) KMT2AMEN1GAAGFERMAPT
SCHEMBL278723 0.69 KAT8 (0.56) KMT2AMEN1GAAGFERMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230125712-A1 SELF-LUMINOUS DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2023-04-27 — — US disclosed
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