SCHEMBL278723

SCHEMBL278723

COC(=O)C(C)n1cc(C=C2C(=O)N(c3ccc(C(=O)O)cc3)N=C2C)c2ccccc21

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KAT8 Q9H7Z6 9/20 0.56
MEN1 O00255 5/20 0.56
KMT2A Q03164 5/20 0.56
MAPT P10636 3/20 0.56
TDP1 Q9NUW8 3/20 0.56
L3MBTL1 Q9Y468 3/20 0.56
MAPK1 P28482 2/20 0.56
LMNA P02545 1/20 0.56
FNTA P49354 1/20 0.51
FNTB P49356 1/20 0.51
EP300 Q09472 8/20 0.50
GAA P10253 2/20 0.46
DHFR P00374 1/20 0.46
GPR55 Q9Y2T6 1/20 0.45
GFER P55789 1/20 0.44
KDM4E B2RXH2 1/20 0.44
USP2 O75604 1/20 0.44
ALDH1A1 P00352 1/20 0.44
POLB P06746 1/20 0.44
SAE1 Q9UBE0 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12126397 1.00 KAT8 (0.56) KAT8MEN1KMT2AMAPTTDP1
SCHEMBL14574109 0.94 MAPT (0.63) KAT8MEN1KMT2AMAPTTDP1
SCHEMBL12128409 0.87 KAT8 (0.53) KAT8MEN1KMT2AMAPTTDP1
SCHEMBL14084870 0.87 KAT8 (0.53) KAT8MEN1KMT2AMAPTTDP1
SCHEMBL12589987 0.82 MAPT (0.82) KAT8MEN1KMT2AMAPTTDP1
SCHEMBL24614118 0.82 KMT2A (0.46) MEN1KMT2AMAPTTDP1L3MBTL1
SCHEMBL22924032 0.82 KMT2A (0.46) MEN1KMT2AMAPTL3MBTL1MAPK1
SCHEMBL26418970 0.82 KMT2A (0.46) MEN1KMT2AMAPTL3MBTL1MAPK1
SCHEMBL22924019 0.82 KMT2A (0.44) MEN1KMT2AMAPTTDP1L3MBTL1
SCHEMBL14462417 0.81 DHFR (0.55) KAT8MEN1KMT2AMAPTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8133665-B2 Silver halide photosensitive material and process of producing black and white image using the same FUJIFILM CORPORATION (JP) 2012-03-13 US disclosed
US-8133665-B2 Silver halide photosensitive material and process of producing black and white image using the same FUJIFILM CORPORATION (JP) 2012-03-13 US disclosed
US-20110070548-A1 SILVER HALIDE PHOTOSENSITIVE MATERIAL AND PROCESS OF PRODUCING BLACK AND WHITE IMAGE USING THE SAME FUJIFILM CORPORATION (JP) 2011-03-24 US disclosed
US-20110070548-A1 SILVER HALIDE PHOTOSENSITIVE MATERIAL AND PROCESS OF PRODUCING BLACK AND WHITE IMAGE USING THE SAME FUJIFILM CORPORATION (JP) 2011-03-24 US disclosed
US-7556918-B2 Color photographic films comprising support having color developable light sensitive silver halide emulsion layers and color dye-forming couplers, used for high speed print reproduction; storage stability FUJIFILM CORPORATION (JP) 2009-07-07 US disclosed
US-7422843-B2 Color photographic films comprising support having color developable light sensitive silver halide emulsion layers and color dye-forming couplers, used for high speed print reproduction; storage stability, cinematography, uniformity for quality FUJIFILM CORPORATION (JP) 2008-09-09 US disclosed
US-20080113305-A1 SILVER HALIDE COLOR PHOTOGRAPHIC LIGHT-SENSITIVE MATERIAL FUJIFILM CORPORATION 2008-05-15 US disclosed
US-20070248906-A1 Silver halide color photographic light-sensitive material FUJIFILM CORPORATION (JP) 2007-10-25 US disclosed
US-7196194-B2 Dye-forming coupler, silver halide photographic light-sensitive material and azomethine dye compound FUJI PHOTO FILM CO., LTD (JP) 2007-03-27 US disclosed
US-7183044-B2 Silver halide color photographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 2007-02-27 US disclosed