Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 3/20 | 0.35 |
| ▸ | HTR2C | P28335 | 4/20 | 0.35 |
| ▸ | HTR2A | P28223 | 3/20 | 0.35 |
| ▸ | DRD2 | P14416 | 2/20 | 0.34 |
| ▸ | DRD3 | P35462 | 2/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | CTSD | P07339 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 2/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22993390 | 0.90 | KDM4E (0.42) | KDM4EBACE1HTR2CHTR2ADRD2 | |
| SCHEMBL26408039 | 0.88 | KDM4E (0.44) | KDM4EBACE1HTR2CHTR2ADRD2 | |
| SCHEMBL24253346 | 0.77 | KDM4E (0.34) | KDM4EBACE1HTR2CHTR2ADRD2 | |
| SCHEMBL24451834 | 0.77 | KDM4E (0.43) | KDM4EBACE1HTR2CHTR2AHTR2B | |
| SCHEMBL24253511 | 0.76 | HTR2C (0.35) | BACE1HTR2CHTR2ADRD2DRD3 | |
| SCHEMBL24124011 | 0.76 | KDM4E (0.48) | KDM4ECYP2D6 | |
| SCHEMBL24329573 | 0.75 | HTR2C (0.48) | HTR2CHTR2ADRD2DRD3CNR1 | |
| SCHEMBL24253542 | 0.75 | HTR2C (0.34) | BACE1HTR2CHTR2ADRD2DRD3 | |
| SCHEMBL24253498 | 0.74 | DRD2 (0.51) | HTR2CHTR2ADRD2DRD3HTR6 | |
| SCHEMBL21671894 | 0.74 | KDM4E (0.47) | KDM4EHTR2ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4169919-A1 | PYRAZOLO[3,4-D]PYRIMIDINE-3-KETONE DERIVATIVE AS WEE-1 INHIBITOR | Wigen Biomedicine Technology (Shanghai) Co., Ltd. (CN) | 2023-04-26 | — | — | EP | disclosed |