Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | F7 | P08709 | 2/20 | 0.39 |
| ▸ | F3 | P13726 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12187705 | 1.00 | ALDH1A1 (0.46) | ALDH1A1CNR1CNR2F7F3 | |
| SCHEMBL14935335 | 1.00 | ALDH1A1 (0.46) | ALDH1A1CNR1CNR2F7F3 | |
| SCHEMBL12186948 | 0.97 | ALDH1A1 (0.47) | ALDH1A1CNR1CNR2F7F3 | |
| SCHEMBL25359611 | 0.96 | CNR1 (0.52) | ALDH1A1CNR1CNR2 | |
| SCHEMBL12187878 | 0.96 | CNR1 (0.52) | ALDH1A1CNR1CNR2 | |
| SCHEMBL21235537 | 0.96 | CNR1 (0.52) | ALDH1A1CNR1CNR2 | |
| SCHEMBL15543930 | 0.96 | CNR1 (0.52) | ALDH1A1CNR1CNR2 | |
| SCHEMBL19909628 | 0.96 | CNR1 (0.52) | ALDH1A1CNR1CNR2 | |
| SCHEMBL2637814 | 0.96 | ALDH1A1 (0.48) | ALDH1A1CNR1CNR2F7F3 | |
| SCHEMBL14935600 | 0.96 | ALDH1A1 (0.48) | ALDH1A1CNR1CNR2F7F3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2569276-A1 | NOVEL CATIONIC LIPIDS AND METHODS OF USE THEREOF | Protiva Biotherapeutics Inc. (CA) | 2013-03-20 | — | — | EP | disclosed |
| WO-2011141705-A1 | NOVEL CATIONIC LIPIDS AND METHODS OF USE THEREOF | PROTIVA BIOTHERAPEUTICS, INC. (CA) | 2011-11-17 | — | — | WO | disclosed |