Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | RAB9A | P51151 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | RELA | Q04206 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | CASP1 | P29466 | 2/20 | 0.50 |
| ▸ | HBB | P68871 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | MAT2A | P31153 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | APP | P05067 | 11/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | S100A4 | P26447 | 1/20 | 0.44 |
| ▸ | INSR | P06213 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2641926 | 1.00 | MAPT (0.57) | MAPTMEN1RAB9AKMT2AKDM4E | |
| SCHEMBL2641792 | 0.83 | EGFR (0.43) | MAPTMEN1RAB9AKMT2AKDM4E | |
| SCHEMBL2641899 | 0.81 | MAPT (0.57) | MAPTMEN1RAB9AKMT2AKDM4E | |
| SCHEMBL12185950 | 0.81 | MAPT (0.57) | MAPTMEN1RAB9AKMT2AKDM4E | |
| SCHEMBL2641835 | 0.81 | MAPT (0.57) | MAPTMEN1RAB9AKMT2AKDM4E | |
| SCHEMBL2641832 | 0.81 | MAPT (0.57) | MAPTMEN1RAB9AKMT2AKDM4E | |
| SCHEMBL2641895 | 0.81 | MAPT (0.57) | MAPTMEN1RAB9AKMT2AKDM4E | |
| SCHEMBL4542155 | 0.79 | GRM4 (0.61) | MAPTMEN1RAB9AKMT2AKDM4E | |
| SCHEMBL4542158 | 0.79 | GRM4 (0.61) | MAPTMEN1RAB9AKMT2AKDM4E | |
| SCHEMBL2641784 | 0.77 | MAPT (0.56) | MAPTMEN1RAB9AKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011141515-A1 | DIAGNOSTIC AGENTS FOR AMYLOID BETA IMAGING | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2011-11-17 | — | — | WO | disclosed |
| WO-2011141515-A1 | DIAGNOSTIC AGENTS FOR AMYLOID BETA IMAGING | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2011-11-17 | — | — | WO | disclosed |