Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2641861 | 0.84 | RAB9A (0.41) | EGFRMEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL2641930 | 0.84 | RAB9A (0.41) | EGFRMEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL2641896 | 0.84 | RAB9A (0.41) | EGFRMEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL12186028 | 0.83 | PAX8 (0.44) | EGFRMEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL2641922 | 0.83 | MAPT (0.57) | EGFRMEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL2641926 | 0.83 | MAPT (0.57) | EGFRMEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL2641783 | 0.80 | MAPT (0.43) | EGFRMEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL2641829 | 0.76 | APP (0.40) | EGFRMEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL4542158 | 0.76 | GRM4 (0.61) | MEN1KMT2AALDH1A1RAB9AKDM4E | |
| SCHEMBL4542155 | 0.76 | GRM4 (0.61) | MEN1KMT2AALDH1A1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011141515-A1 | DIAGNOSTIC AGENTS FOR AMYLOID BETA IMAGING | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2011-11-17 | — | — | WO | claimed |
| WO-2011141515-A1 | DIAGNOSTIC AGENTS FOR AMYLOID BETA IMAGING | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2011-11-17 | — | — | WO | disclosed |