Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26419912 | 0.84 | CRHBP (0.38) | CRHBPCRHR2 | |
| SCHEMBL24995128 | 0.77 | — | — | |
| SCHEMBL26419104 | 0.75 | CRHBP (0.38) | CRHBPCRHR2 | |
| SCHEMBL20434854 | 0.73 | CRHBP (0.41) | CRHBPCRHR2 | |
| SCHEMBL19498072 | 0.71 | CRHBP (0.38) | CRHBPCRHR2 | |
| SCHEMBL26419299 | 0.68 | CRHBP (0.36) | CRHBPCRHR2 | |
| SCHEMBL680047 | 0.67 | CRHBP (0.39) | CRHBPCRHR2 | |
| SCHEMBL20434848 | 0.66 | CRHBP (0.36) | CRHBPCRHR2 | |
| SCHEMBL26419482 | 0.66 | CRHBP (0.34) | CRHBPCRHR2 | |
| SCHEMBL24091654 | 0.65 | CRHBP (0.33) | CRHBPCRHR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230128824-A1 | SPIRO RING-CONTAINING QUINAZOLINE COMPOUND | Wigen Biomedicine Technology (shanghai) Co., Ltd. (CN) | 2023-04-27 | — | — | US | disclosed |
| US-20230128824-A1 | SPIRO RING-CONTAINING QUINAZOLINE COMPOUND | Wigen Biomedicine Technology (shanghai) Co., Ltd. (CN) | 2023-04-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230128824-A1 | SPIRO RING-CONTAINING QUINAZOLINE COMPOUND | KRAS, NRAS, HRAS | CRHBP 3609/4885CRHR2 3865/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.