Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 6/20 | 0.58 |
| ▸ | HPGD | P15428 | 9/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | RXRA | P19793 | 1/20 | 0.51 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2641985 | 0.83 | HPGD (0.47) | FGFR1HPGDALDH1A1LMNATSHR | |
| SCHEMBL23675169 | 0.79 | FGFR1 (0.77) | FGFR1HPGDALDH1A1THRB | |
| SCHEMBL2642038 | 0.77 | GABRP (0.46) | FGFR1HPGD | |
| SCHEMBL28685131 | 0.75 | FGFR1 (0.85) | FGFR1HPGDALDH1A1LMNATHRB | |
| SCHEMBL29987340 | 0.75 | FGFR1 (0.85) | FGFR1HPGDALDH1A1LMNATHRB | |
| SCHEMBL4505231 | 0.74 | FGFR1 (0.78) | FGFR1HPGDALDH1A1LMNATHRB | |
| SCHEMBL2365060 | 0.74 | HPGD (0.70) | FGFR1HPGDALDH1A1LMNATHRB | |
| SCHEMBL28288329 | 0.74 | HPGD (0.70) | FGFR1HPGDALDH1A1LMNATHRB | |
| SCHEMBL2339842 | 0.74 | HPGD (0.70) | FGFR1HPGDALDH1A1LMNATHRB | |
| SCHEMBL122653 | 0.74 | FGFR1 (1.00) | FGFR1HPGDALDH1A1LMNATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0563001-B1 | Imidazole compounds, their preparation and use | NEUROSEARCH AS (DK) | 1996-02-28 | — | — | EP | disclosed |
| US-5360809-A | Imidazole compounds and their use as calcium channel blockers | NEUROSEARCH A/S (DK) | 1994-11-01 | — | — | US | disclosed |
| EP-0563001-A1 | Imidazole compounds, their preparation and use | NEUROSEARCH A/S (DK) | 1993-09-29 | — | — | EP | disclosed |