Sugi Predict

Sugi Predict / Compounds / SCHEMBL26422112

SCHEMBL26422112

SCHEMBL26422112

CC(=O)N[C@@H](CC(=O)O)C(=O)N[C@H]1CSSC[C@@H](C(N)=O)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](C(C)C)CC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](C)NC1=O

nearest known ligand 0.57

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ TSLP Q969D9 19/20 0.57
▸ MC4R P32245 1/20 0.54
▸ MC5R P33032 1/20 0.54
▸ MC3R P41968 1/20 0.54
▸ MC1R Q01726 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26428173 0.93 TSLP (0.58) TSLPMC4RMC5RMC3RMC1R
SCHEMBL26428192 0.90 TSLP (0.58) TSLPMC4RMC5RMC3RMC1R
SCHEMBL26417485 0.89 SSTR2 (0.49) TSLPMC4RMC5RMC3RMC1R
SCHEMBL26422090 0.89 TSLP (0.54) TSLPMC4RMC5RMC3RMC1R
SCHEMBL23417726 0.85 SSTR2 (0.52) TSLP
SCHEMBL26422370 0.84 SSTR2 (0.49) TSLPMC4RMC5RMC3RMC1R
SCHEMBL26422376 0.84 SSTR2 (0.49) TSLPMC4RMC5RMC3RMC1R
SCHEMBL23417758 0.84 SSTR2 (0.55) TSLP
SCHEMBL23417835 0.83 TSLP (0.49) TSLPMC4RMC5RMC3RMC1R
SCHEMBL23417755 0.83 SSTR2 (0.50) TSLP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230128688-A1 DIRECTED CONJUGATION TECHNOLOGIES KLEO PHARMACEUTICALS, INC. 2023-04-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230128688-A1 DIRECTED CONJUGATION TECHNOLOGIES CD2BP2, CD2, CD47 TSLP 2990/4885MC4R 4124/4885MC5R 3989/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.