SCHEMBL264229

SCHEMBL264229

NC(=O)CCC(=O)NCl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29022190 0.86 HDAC3 (0.42)
SCHEMBL4137033 0.85 PHF8 (0.38)
SCHEMBL29022101 0.84 HDAC3 (0.46)
SCHEMBL4258637 0.79 CYP3A4 (0.41)
SCHEMBL11875428 0.77
Succinamide SCHEMBL36057 0.74
Succinamide SCHEMBL28157588 0.74 LMNA (0.50)
SCHEMBL137189 0.74
SCHEMBL14967033 0.74
SCHEMBL27643837 0.74 FOLH1 (0.57)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1497 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12084457-B2 Methods for the preparation of 1,3-benzodioxole heterocyclic compounds UNION therapeutics A/S (DK) 2024-09-10 US claimed
CN-118344381-A Process for preparing 1, 3-benzodioxole heterocyclic compounds 联合疗法公司 2024-07-16 CN claimed
CN-113024372-A Synthetic method of 2-chloro-3-fluoro-4-trifluoromethyl benzoyl chloride 内蒙古蓝科生物科技有限公司 2021-06-25 CN claimed
CN-112480540-A Regenerated plastic particle modification process 界首市聚屹包装材料有限公司 2021-03-12 CN claimed
CN-105503882-B The method for preparing S1P1 receptor modulators and its crystal form 艾尼纳制药公司 2019-07-05 CN claimed
CN-106068121-A Clomiphene synthesis using a single solvent 利普生物药剂公司 2016-11-02 CN claimed
US-9212150-B2 Process for the preparation of certain triaryl pesticide intermediates DOW AGROSCIENCES LLC (US) 2015-12-15 US claimed
WO-2015092739-A1 PROCESS FOR PREPARATION OF ALOGLIPTIN Mylan Laboratories Ltd. (IN) 2015-06-25 WO claimed
US-20140275557-A1 PROCESS FOR THE PREPARATION OF CERTAIN TRIARYL PESTICIDE INTERMEDIATES DOW AGROSCIENCES LLC (US) 2014-09-18 US claimed
WO-2014016847-A1 A PROCESS FOR THE PREPARATION OF CINACALCET HYDROCHLORIDE AND ITS INTERMEDIATE TYCHE INDUSTRIES LIMITED (IN) 2014-01-30 WO claimed
WO-2003082895-A2 PROCESS TO PREPARE EPLERENONE PHARMACIA & UPJOHN COMPANY (US) 2003-10-09 WO claimed
US-6620972-B2 Fluorous sulfoxides used to oxidize primary or secondary alcohols to aldehydes or ketones in presence of activator, followed by treatment with organic base THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS 2003-09-16 US claimed
US-20030105363-A1 Method of oxidizing an alcohol using a recyclable fluorous sulfoxide UNIVERSITY OF ILLINOIS AT CHICAGO 2003-06-05 US claimed
WO-2003002526-A1 METHOD OF OXIDIZING AN ALCOHOL USING A RECYCLABLE FLUOROUS SULFOXIDE THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2003-01-09 WO claimed
EP-0880490-A4 SYNTHESIS OF PERFLUORO AROMATIC BORANES AND BORATES BOULDER SCIENT CO (US) 2000-05-10 EP claimed
EP-0880490-A1 SYNTHESIS OF PERFLUORO AROMATIC BORANES AND BORATES BOULDER SCIENTIFIC COMPANY (US) 1998-12-02 EP claimed
WO-1998017611-A1 SYNTHESIS OF PERFLUORO AROMATIC BORANES AND BORATES BOULDER SCIENTIFIC COMPANY (US) 1998-04-30 WO claimed
US-5744656-A Conversion of hexafluorobenzene to bromopentafluorobenzene BOULDER SCIENTIFIC COMPANY (US) 1998-04-28 US claimed
EP-0378357-A1 Anti-inflammatory 1-heteroaryloxindole-3-carboxamides PFIZER INC. (US) 1990-07-18 EP claimed
EP-0378358-A1 Anti-inflammmatory 1-heteroaryl-3-acyl-2-oxindoles PFIZER INC. (US) 1990-07-18 EP claimed