SCHEMBL26423262

SCHEMBL26423262

c1cc2cc3oc4ccncc4c3cc2cn1

nearest known ligand 0.41

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HASPIN Q8TF76 12/20 0.41
PIM1 P11309 4/20 0.41
CCNT1 O60563 4/20 0.41
CDK9 P50750 4/20 0.41
CLK1 P49759 2/20 0.41
GRM4 Q14833 1/20 0.37
CSNK1D P48730 1/20 0.37
CSNK1E P49674 1/20 0.37
DYRK1A Q13627 1/20 0.37
PRKCZ Q05513 1/20 0.35
KDM4E B2RXH2 1/20 0.35
POLB P06746 1/20 0.35
HTT P42858 1/20 0.35
RAD52 P43351 1/20 0.35
MAOA P21397 1/20 0.33
CYP19A1 P11511 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26423264 1.00 HASPIN (0.41) HASPINPIM1CCNT1CDK9CLK1
SCHEMBL13085116 0.89 KDM4E (0.39) HASPINCLK1GRM4KDM4EPOLB
SCHEMBL17756864 0.86 CLK1 (0.49) HASPINPIM1CCNT1CDK9CLK1
SCHEMBL26423191 0.86 CLK1 (0.49) HASPINPIM1CCNT1CDK9CLK1
SCHEMBL26423254 0.86 HASPIN (0.41) HASPINPIM1CCNT1CDK9CLK1
SCHEMBL26423256 0.86 HASPIN (0.41) HASPINPIM1CCNT1CDK9CLK1
SCHEMBL24910922 0.83 AHR (0.53) HASPINPIM1CCNT1CDK9CLK1
SCHEMBL24911407 0.83 AHR (0.53) HASPINPIM1CCNT1CDK9CLK1
SCHEMBL24911214 0.82 AHR (0.44) KDM4EHTTCYP19A1
SCHEMBL24911473 0.82 AHR (0.44) KDM4EHTTCYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230127291-A1 HETEROCYCLIC ARYLAMINE COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE AND DISPLAY PANEL WUHAN TIANMA MICROELECTRONICS CO., LTD. (CN) 2023-04-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230127291-A1 HETEROCYCLIC ARYLAMINE COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE AND DISPLAY PANEL OCIAD2, OCIAD1, AZI2 HASPIN 2934/4885PIM1 3895/4885CCNT1 561/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.