Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK1 | P49759 | 1/20 | 0.49 |
| ▸ | AHR | P35869 | 2/20 | 0.47 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | HASPIN | Q8TF76 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAD52 | P43351 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17756864 | 1.00 | CLK1 (0.49) | CLK1AHRGRM4MAPTNPC1 | |
| SCHEMBL24910807 | 0.89 | MAPT (0.41) | CLK1AHRGRM4MAPTNPC1 | |
| SCHEMBL24910806 | 0.87 | MAPT (0.39) | CLK1AHRGRM4MAPTNPC1 | |
| SCHEMBL26423262 | 0.86 | HASPIN (0.41) | CLK1GRM4KDM4EHASPINPOLB | |
| SCHEMBL26423264 | 0.86 | HASPIN (0.41) | CLK1GRM4KDM4EHASPINPOLB | |
| SCHEMBL26423254 | 0.86 | HASPIN (0.41) | CLK1HASPINPIM1CCNT1CDK9 | |
| SCHEMBL26423256 | 0.86 | HASPIN (0.41) | CLK1HASPINPIM1CCNT1CDK9 | |
| SCHEMBL17756846 | 0.83 | HASPIN (0.48) | CLK1HASPINPIM1CCNT1CDK9 | |
| SCHEMBL13085116 | 0.83 | KDM4E (0.39) | CLK1AHRGRM4MAPTNPC1 | |
| SCHEMBL26423203 | 0.83 | ROCK2 (0.44) | CLK1AHRMAPTNPC1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230127291-A1 | HETEROCYCLIC ARYLAMINE COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE AND DISPLAY PANEL | WUHAN TIANMA MICROELECTRONICS CO., LTD. (CN) | 2023-04-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230127291-A1 | HETEROCYCLIC ARYLAMINE COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE AND DISPLAY PANEL | OCIAD2, OCIAD1, AZI2 | CLK1 4489/4885AHR 19/4885GRM4 2835/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.