SCHEMBL26424236

SCHEMBL26424236

C=NC(=O)CCCC(N)=O

nearest known ligand 0.31

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.31
TP53 P04637 2/20 0.31
CYP1A2 P05177 2/20 0.31
CYP3A4 P08684 2/20 0.31
CYP2C19 P33261 2/20 0.31
MEN1 O00255 1/20 0.31
FAAH O00519 1/20 0.31
SOAT1 P35610 1/20 0.31
ALOX15 P16050 2/20 0.31
BLM P54132 2/20 0.31
PMP22 Q01453 2/20 0.31
SLC22A6 Q4U2R8 1/20 0.30
KDM4E B2RXH2 1/20 0.30
GMNN O75496 1/20 0.30
USP2 O75604 1/20 0.30
ALDH1A1 P00352 1/20 0.30
LMNA P02545 1/20 0.30
GLA P06280 1/20 0.30
POLB P06746 1/20 0.30
CYP2C9 P11712 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1291922 0.95 KMT2A (0.35) KMT2ATP53CYP1A2CYP3A4CYP2C19
SCHEMBL1160173 0.92 KMT2A (0.39) KMT2ATP53CYP1A2CYP3A4CYP2C19
SCHEMBL9853145 0.92 KMT2A (0.39) KMT2ATP53CYP1A2CYP3A4CYP2C19
SCHEMBL26424544 0.86
SCHEMBL26412993 0.79 SLC22A6 (0.58) KMT2ACYP1A2BLMPMP22SLC22A6
SCHEMBL984694 0.76
SCHEMBL16672200 0.76 KMT2A (0.32) KMT2ATP53CYP1A2CYP3A4CYP2C19
SCHEMBL16484785 0.75 LMNA (0.52) KMT2ACYP1A2MEN1ALOX15BLM
SCHEMBL8921255 0.73 KMT2A (0.46) KMT2ATP53CYP1A2CYP3A4CYP2C19
Hydrochloric Acid SCHEMBL5736439 0.73 LMNA (0.44) KMT2ATP53CYP1A2CYP3A4CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4170347-A1 GASTRIC INHIBITORY PEPTIDE RECEPTOR LIGANDS 3B Pharmaceuticals GmbH (DE) 2023-04-26 EP disclosed