SCHEMBL26425645

SCHEMBL26425645

Cc1ccc(N2CC(C)C2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRB1 P08588 1/20 0.48
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
POLB P06746 1/20 0.40
F2 P00734 1/20 0.39
ELANE P08246 1/20 0.39
CTSG P08311 1/20 0.39
CMA1 P23946 1/20 0.39
CTRC Q99895 1/20 0.39
ACHE P22303 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
NPY1R P25929 1/20 0.38
AKR1C3 P42330 1/20 0.38
MAPT P10636 4/20 0.38
ALDH1A1 P00352 1/20 0.37
CYP1A2 P05177 1/20 0.37
GAA P10253 1/20 0.37
RAB9A P51151 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
MGLL Q99685 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18435971 0.91 MEN1 (0.53) ADRB1MEN1KMT2APOLBF2
SCHEMBL18436659 0.91 MEN1 (0.53) ADRB1MEN1KMT2APOLBF2
SCHEMBL19012555 0.91 MEN1 (0.53) ADRB1MEN1KMT2APOLBF2
SCHEMBL19314278 0.83 USP2 (0.47) ADRB1MEN1KMT2AAKR1C3MAPT
SCHEMBL8280718 0.82 ADRB1 (0.45) ADRB1MEN1KMT2AF2ELANE
SCHEMBL24352865 0.80 MAPT (0.57) ADRB1KMT2APOLBMAPTALDH1A1
SCHEMBL81349 0.80 ADRB1 (0.48) ADRB1MEN1KMT2AMAPTALDH1A1
SCHEMBL81695 0.80 ADRB1 (0.48) ADRB1MEN1KMT2AMAPTALDH1A1
SCHEMBL7790503 0.80 MAPT (0.57) ADRB1KMT2APOLBMAPTALDH1A1
SCHEMBL82062 0.80 ADRB1 (0.44) ADRB1MEN1KMT2AF2ELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111233752-B Decarboxylation in-situ methylation method of alkyl active carboxylic ester 中国科学技术大学 2021-07-09 CN disclosed
CN-111233752-A Decarboxylation in-situ methylation method of alkyl active carboxylic ester 中国科学技术大学 2020-06-05 CN disclosed