Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CXCR4 | P61073 | 5/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | CCR2 | P41597 | 1/20 | 0.31 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25045105 | 0.93 | HTR6 (0.68) | HTR6KMT2ASMN1; SMN2HPGDCXCR4 | |
| SCHEMBL5071333 | 0.90 | HTR6 (0.56) | HTR6KMT2ASMN1; SMN2HPGD | |
| SCHEMBL24684499 | 0.85 | HTR6 (0.70) | HTR6KMT2ASMN1; SMN2HPGDCXCR4 | |
| SCHEMBL64117 | 0.83 | HTR6 (0.56) | HTR6KMT2ASMN1; SMN2HPGDCXCR4 | |
| SCHEMBL2904654 | 0.83 | HTR6 (0.56) | HTR6KMT2ASMN1; SMN2HPGDCXCR4 | |
| SCHEMBL337087 | 0.82 | HTR6 (0.65) | HTR6KMT2ASMN1; SMN2HPGD | |
| SCHEMBL3056808 | 0.82 | — | — | |
| SCHEMBL3810047 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL2973444 | 0.81 | HTR6 (0.54) | HTR6KMT2ASMN1; SMN2HPGDCXCR4 | |
| SCHEMBL1507120 | 0.81 | HTR6 (0.65) | HTR6KMT2ASMN1; SMN2HPGDCXCR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023067353-A1 | HETEROCYCLIC COMPOUNDS FOR USE IN THE TREATMENT OF CANCER | ARTIOS PHARMA LIMITED (GB) | 2023-04-27 | — | — | WO | disclosed |