Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31284724 | 0.89 | CNR2 (0.44) | CNR2MAPTCYP1A2SMN1; SMN2GAA | |
| SCHEMBL23530104 | 0.86 | CNR2 (0.54) | CNR2MAPTCYP1A2SMN1; SMN2GAA | |
| SCHEMBL410932 | 0.85 | CNR2 (0.49) | CNR2MAPTCYP1A2SMN1; SMN2GAA | |
| SCHEMBL412412 | 0.78 | CNR2 (0.49) | CNR2MAPTCYP1A2SMN1; SMN2GAA | |
| SCHEMBL22235457 | 0.77 | CNR2 (0.50) | CNR2MAPTCYP1A2SMN1; SMN2GAA | |
| SCHEMBL23106869 | 0.76 | CNR2 (0.34) | CNR2CHRNB2CHRNA4PARP1 | |
| SCHEMBL27372368 | 0.76 | CNR2 (0.49) | CNR2MAPTCYP1A2SMN1; SMN2GAA | |
| SCHEMBL30755591 | 0.76 | CNR2 (0.49) | CNR2MAPTCYP1A2SMN1; SMN2GAA | |
| SCHEMBL69653 | 0.76 | MAPT (0.64) | MAPTCYP1A2SMN1; SMN2GAARECQL | |
| SCHEMBL17478778 | 0.75 | CNR2 (0.43) | CNR2MAPTCYP1A2SMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023067353-A1 | HETEROCYCLIC COMPOUNDS FOR USE IN THE TREATMENT OF CANCER | ARTIOS PHARMA LIMITED (GB) | 2023-04-27 | — | — | WO | disclosed |