Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 6/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.40 |
| ▸ | AXL | P30530 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.38 |
| ▸ | KDM5A | P29375 | 1/20 | 0.38 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17478650 | 0.84 | KDM4E (0.44) | CNR2MAP4K4KDM5A | |
| SCHEMBL412412 | 0.83 | CNR2 (0.49) | CNR2CYP1A2NPC1TP53CYP3A4 | |
| SCHEMBL23530104 | 0.82 | CNR2 (0.54) | CNR2CYP1A2NPC1TP53CYP3A4 | |
| SCHEMBL411915 | 0.79 | CNR2 (0.45) | CNR2CYP1A2NPC1TP53CYP3A4 | |
| SCHEMBL13490509 | 0.78 | BCHE (0.51) | CYP1A2CYP3A4CYP2C9DRD2DRD4 | |
| SCHEMBL410932 | 0.76 | CNR2 (0.49) | CNR2CYP1A2NPC1TP53CYP3A4 | |
| SCHEMBL1557415 | 0.76 | TRPV3 (0.48) | CNR2MAPT | |
| SCHEMBL26428540 | 0.75 | CNR2 (0.45) | CNR2CYP1A2NPC1TP53CYP3A4 | |
| SCHEMBL22235457 | 0.74 | CNR2 (0.50) | CNR2CYP1A2NPC1TP53CYP3A4 | |
| SCHEMBL31284724 | 0.74 | CNR2 (0.44) | CNR2CYP1A2NPC1TP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3174868-A1 | COMPOUNDS ACTIVE TOWARDS BROMODOMAINS | Nuevolution A/S (DK) | 2017-06-07 | — | — | EP | disclosed |
| WO-2016016316-A1 | COMPOUNDS ACTIVE TOWARDS BROMODOMAINS | NUEVOLUTION A/S (DK) | 2016-02-04 | — | — | WO | disclosed |