SCHEMBL26428903

SCHEMBL26428903

c1ccc([Si](c2ccccc2)(c2ccccc2)c2cccc(-c3ccc(-n4c5ccccc5c5cc(-n6c7ccccc7c7ccccc76)ccc54)cc3)c2)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.45
KDM4E B2RXH2 1/20 0.45
ATM Q13315 1/20 0.45
HDAC4 P56524 1/20 0.38
RAC2 P15153 1/20 0.37
RAC3 P60763 1/20 0.37
CDC42 P60953 1/20 0.37
RAC1 P63000 1/20 0.37
TSPO P30536 2/20 0.36
NR3C1 P04150 1/20 0.34
PTPN1 P18031 2/20 0.34
EDNRB P24530 1/20 0.34
EDNRA P25101 1/20 0.34
KMT2A Q03164 3/20 0.33
IL1R1 P14778 1/20 0.33
MEN1 O00255 2/20 0.33
MAPT P10636 2/20 0.33
ALDH1A1 P00352 1/20 0.33
HTT P42858 1/20 0.33
PTGER4 P35408 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25449255 0.97 L3MBTL1 (0.45) L3MBTL1KDM4EATMHDAC4RAC2
SCHEMBL26762046 0.96 L3MBTL1 (0.47) L3MBTL1KDM4EATMHDAC4RAC2
SCHEMBL26762049 0.96 L3MBTL1 (0.47) L3MBTL1KDM4EATMHDAC4RAC2
SCHEMBL18779593 0.96 L3MBTL1 (0.46) L3MBTL1KDM4EATMHDAC4RAC2
SCHEMBL18805005 0.96 L3MBTL1 (0.46) L3MBTL1KDM4EATMHDAC4RAC2
SCHEMBL26519077 0.96 L3MBTL1 (0.46) L3MBTL1KDM4EATMHDAC4RAC2
SCHEMBL26762054 0.95 ATM (0.42) L3MBTL1KDM4EATMHDAC4RAC2
SCHEMBL26716250 0.95 L3MBTL1 (0.42) L3MBTL1KDM4EATMHDAC4RAC2
SCHEMBL18805007 0.95 L3MBTL1 (0.46) L3MBTL1KDM4EATMHDAC4RAC2
SCHEMBL18805015 0.95 L3MBTL1 (0.46) L3MBTL1KDM4EATMHDAC4RAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230127039-A1 LIGHT EMITTING ELEMENT SAMSUNG DISPLAY CO., LTD. (KR) 2023-04-27 US disclosed
US-20230127039-A1 LIGHT EMITTING ELEMENT SAMSUNG DISPLAY CO., LTD. (KR) 2023-04-27 US disclosed