⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2642831 | 0.81 | TAAR1 (0.57) | — | |
| SCHEMBL36008 | 0.81 | LOXL2 (0.71) | — | |
| SCHEMBL10422276 | 0.81 | LOXL2 (0.71) | — | |
| SCHEMBL29575625 | 0.78 | LOXL2 (0.67) | — | |
| Ammonia Solution, Strong SCHEMBL6899866 | 0.78 | LOXL2 (0.67) | — | |
| Bromide SCHEMBL28362115 | 0.78 | LOXL2 (0.67) | — | |
| Hydrochloric Acid SCHEMBL8195914 | 0.78 | LOXL2 (0.67) | — | |
| Hydrochloric Acid SCHEMBL6018896 | 0.78 | LOXL2 (0.67) | — | |
| SCHEMBL7883952 | 0.78 | LOXL2 (0.67) | — | |
| Bromide SCHEMBL29013587 | 0.78 | LOXL2 (0.67) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107522634-A | Biaryl ureas carboxylic acid derivates or its salt and its production and use | 复旦大学 | 2017-12-29 | — | — | CN | disclosed |
| CN-102341175-B | Selective hydrogenation catalyst and preparation and application thereof | Chevron Phillips Chemical Co.,L.P. (US) | 2016-11-30 | — | — | CN | disclosed |
| CN-101160049-B | Spiroketal-substituted cyclic ketoenols | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-05-11 | — | — | CN | disclosed |
| US-8765789-B2 | 2-pyridinecarboxamide derivatives | MSD K.K. (JP) | 2014-07-01 | — | — | US | disclosed |
| US-20130085156-A1 | NOVEL 2-PYRIDINECARBOXAMIDE DERIVATIVES | MSD K.K. (JP) | 2013-04-04 | — | — | US | disclosed |
| US-8344003-B2 | 2-pyridinecarboxamide derivatives | MSD K. K. (JP) | 2013-01-01 | — | — | US | disclosed |
| US-20100041660-A1 | NOVEL 2-PYRIDINECARBOXAMIDE DERIVATIVES | MSD K.K. (JP) | 2010-02-18 | — | — | US | disclosed |
| US-7629362-B2 | 2-pyridine carboxamide derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2009-12-08 | — | — | US | disclosed |
| US-20060258701-A1 | Novel 2-pyridinecarboxamide derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2006-11-16 | — | — | US | disclosed |
| EP-1598349-A1 | NOVEL 2-PYRIDINECARBOXAMIDE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2005-11-23 | — | — | EP | disclosed |
| CN-1553900-A | Acylsemicarbazides as cyclin dependent kinase inhibitors useful as anti-cancer and anti-proliferative agents | ��ʱ��ʩ����ҩ��˾ | 2004-12-08 | — | — | CN | disclosed |
| CN-1121421-C | (CO) polymers by photopolymerization | CIBA SC HOLDING AG (CH) | 2003-09-17 | — | — | CN | disclosed |
| CN-1248267-A | (Co) polymers by photopolymerization | CIBA SC HOLDING AG (CH) | 2000-03-22 | — | — | CN | disclosed |
| CN-1046507-C | Heterocyclic compounds for the treatment of central nervous system and cardiovascular diseases | UPJOHN CO (US) | 1999-11-17 | — | — | CN | disclosed |
| CN-1139431-A | Heterocyclic compounds for the treatment of central nervous system and cardiovascular diseases | PHARMACIA & UPJOHN CO LLC (US) | 1997-01-01 | — | — | CN | disclosed |