Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | HRH2 | P25021 | 1/20 | 0.53 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25530345 | 1.00 | USP2 (0.53) | USP2LMNAHRH2GPR84HCAR2 | |
| SCHEMBL18649060 | 1.00 | USP2 (0.53) | USP2LMNAHRH2GPR84HCAR2 | |
| SCHEMBL658444 | 0.98 | USP2 (0.55) | USP2LMNAHRH2GPR84HCAR2 | |
| SCHEMBL4629926 | 0.92 | — | — | |
| SCHEMBL4222977 | 0.83 | — | — | |
| SCHEMBL24566374 | 0.77 | USP2 (0.42) | USP2LMNAHRH2CYP1A2CYP3A4 | |
| SCHEMBL4711257 | 0.75 | — | — | |
| SCHEMBL25421446 | 0.75 | — | — | |
| SCHEMBL12988348 | 0.74 | USP2 (0.52) | USP2LMNAHRH2HCAR2CYP1A2 | |
| SCHEMBL241536 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE49517-E1 | Pyrazoles | Janssen Pharmaceuticals, Inc. (US) | 2023-05-02 | — | — | US | disclosed |