SCHEMBL2643285

SCHEMBL2643285

Cc1cnccc1S

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2642738 0.79
SCHEMBL64272 0.75
SCHEMBL29470901 0.75
SCHEMBL5668716 0.75 SIRT3 (0.48)
SCHEMBL5949528 0.75
SCHEMBL21254307 0.73 PSMD14 (0.43)
SCHEMBL34469171 0.72
SCHEMBL29245412 0.72 SIRT3 (0.46)
SCHEMBL29452995 0.72
Hydrochloric Acid SCHEMBL28967061 0.72 SIRT3 (0.46)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118271290-A Continuous flow preparation method of trithio s-triazine compound 上海沃凯生物技术有限公司 2024-07-02 CN claimed
CN-108727902-A Inorganic nano material prints ink and preparation method thereof TCL集团股份有限公司 2018-11-02 CN claimed
CN-118271290-A Continuous flow preparation method of trithio s-triazine compound 上海沃凯生物技术有限公司 2024-07-02 CN disclosed
WO-2023205595-A2 EGFR INHIBITORS IN CANCER TREATMENT CELYN THERAPEUTICS, INC (US) 2023-10-26 WO disclosed
US-20230212160-A1 2,4,6-TRI-SUBSTITUTED PYRIMIDINE COMPOUNDS AS ATR KINASE INHIBITORS BEIJING TIDE PHARMACEUTICAL CO., LTD. (CN) 2023-07-06 US disclosed
WO-2023125737-A1 HETEROCYCLIC COMPOUNDS AND USE THEREOF SILEXON AI TECHNOLOGY CO., LTD. (CN) 2023-07-06 WO disclosed
US-20230183237-A1 COMPETITIVE AND NONCOMPETITIVE INHIBITORS OF THE MUSCARINIC ACETYLCHOLINE RECEPTOR M5 VANDERBILT UNIVERSITY 2023-06-15 US disclosed
WO-2021024141-A1 PREVENTION OR TREATMENT OF DISEASES AND DISORDERS ASSOCIATED WITH TISSUE DAMAGE LI XIAOXIANG (CN) 2021-02-11 WO disclosed
US-20170114067-A1 METHOD OF TREATMENT USING SUBSTITUTED PYRAZOLO[1,5-A] PYRIMIDINE COMPOUNDS ARRAY BIOPHARMA, INC. 2017-04-27 US disclosed
US-8765789-B2 2-pyridinecarboxamide derivatives MSD K.K. (JP) 2014-07-01 US disclosed
US-20130085156-A1 NOVEL 2-PYRIDINECARBOXAMIDE DERIVATIVES MSD K.K. (JP) 2013-04-04 US disclosed
US-20100041660-A1 NOVEL 2-PYRIDINECARBOXAMIDE DERIVATIVES MSD K.K. (JP) 2010-02-18 US disclosed
US-7629362-B2 2-pyridine carboxamide derivatives BANYU PHARMACEUTICAL CO., LTD. (JP) 2009-12-08 US disclosed
US-20080070928-A1 Novel 2-Heteroaryl-Substituted Benzimidazole Derivative MSD K.K. (JP) 2008-03-20 US disclosed
US-20060258701-A1 Novel 2-pyridinecarboxamide derivatives BANYU PHARMACEUTICAL CO., LTD. (JP) 2006-11-16 US disclosed
EP-1702919-A1 NOVEL 2-HETEROARYL-SUBSTITUTED BENZIMIDAZOLE DERIVATIVE BANYU PHARMACEUTICAL CO., LTD. (JP) 2006-09-20 EP disclosed
EP-1598349-A1 NOVEL 2-PYRIDINECARBOXAMIDE DERIVATIVES BANYU PHARMACEUTICAL CO., LTD. (JP) 2005-11-23 EP disclosed
US-4764606-A CHEMICAL INTERMEDIATED YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) 1988-08-16 US disclosed
EP-0212893-A2 7-Formylaminocephalosporin compounds and microorganism and process for their production YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) 1987-03-04 EP disclosed
US-3969526-A Anthelmintic 5-heterocycliothio and oxy-2-carbalkoxyaminobenzimidazles SMITHKLINE CORPORATION (US) 1976-07-13 US disclosed