Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL1B | P01584 | 11/20 | 0.49 |
| ▸ | TNF | P01375 | 2/20 | 0.49 |
| ▸ | HTR1A | P08908 | 3/20 | 0.41 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.40 |
| ▸ | SYK | P43405 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.34 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.33 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26091725 | 0.91 | IL1B (0.49) | IL1BTNFHTR1ANLRP3SYK | |
| SCHEMBL26434714 | 0.91 | IL1B (0.49) | IL1BTNFHTR1ANLRP3SYK | |
| SCHEMBL30374753 | 0.91 | IL1B (0.49) | IL1BTNFHTR1ANLRP3SYK | |
| SCHEMBL26093850 | 0.87 | IL1B (0.67) | IL1BTNFNLRP3KCNH2 | |
| SCHEMBL26434712 | 0.87 | IL1B (0.67) | IL1BTNFNLRP3KCNH2 | |
| SCHEMBL26434708 | 0.80 | IL1B (0.42) | IL1BTNFNLRP3 | |
| SCHEMBL26434217 | 0.77 | IL1B (0.49) | IL1BTNFHTR1ANLRP3SYK | |
| SCHEMBL26434706 | 0.76 | IL1B (0.70) | IL1BNLRP3 | |
| SCHEMBL26434709 | 0.76 | IL1B (0.51) | IL1BTNFNLRP3 | |
| SCHEMBL26089652 | 0.74 | IL1B (0.43) | IL1BTNFHTR1ANLRP3SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023066377-A1 | NITROGEN-CONTAINING COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 索智生物科技（浙江）有限公司 | 2023-04-27 | — | — | WO | disclosed |